| In this study,breeding sows were fed with astragalus polysaccharides and probiotics to investigate the effects of astragalus polysaccharides and probiotics on performance,immunity and Antioxidation of sows,to provide the basic data for producers to select the product of animal protection in breeding sows.A single-factor randomized trial design was adopted in this study.100 Landrace×Yorkshire sows of similar blood relationship,parity and body weight were selected.After breeding,76 sows were randomly selected and assigned to two treatments,38 replicates per treatment and 1 pig per replicate.The two groups were:control group(basic diet)and APSC group(basic diet+Astragalus polysaccharide complex package:Astragalus polysaccharide:160mg/kg;compound probiotics:Bacillus subtilis,Enterococcus faecalis,Lactobacillus,viable count>5×10~8CFU/kg).The period of the study was from gestation to lactation.The results showed that:1.The effects of APSC on productive performance of sows:Adding APSC to the diet can significantly increase the total feed intake of sows in the early lactation stage(first week),middle lactation stage(second week),and whole lactation stage(P<0.05),and significantly increase the feed intake in the late lactation stage(third week)(P<0.01).There is a trend of decreasing back fat loss in sows during lactation stage(P=0.064).2.The effects of APSC on reproductive performance of sows:The APSC group increased the number of live births by 6.1%compared to the CON group,significantly reducing the number of Stillborn and the incidence of IUGR rate(P<0.05),and significantly reducing the Stillborn rate(P<0.01).And the incidence of postpartum syndrome in sows and the intervention rate for labor assistance decreased by 52%and 44%,respectively(P>0.1).3.The effects on the composition of sows milk:Compared with the CON group,the protein content in colostrum of sows fed with APSC showed an increasing trend(P=0.07),and the IgA content in colostrum of sows fed with APSC was significantly higher than that of the control group(P=0.003).4.The effects on antioxidant capacity of sows and piglets:The GSH-Px content in the plasma of sows before and after delivery with the addition of APSC in the diet significantly increased(P<0.05),and the GSH-Px content in the plasma significantly increased(P<0.01)on the day of delivery.There was a trend of increasing T-SOD content in the plasma of sows on the day of delivery and L7(0.05≤P<0.1),and a significant decrease in MDA content in the plasma of sows on the day of delivery(P<0.05).There was a trend of decreasing MDA content in the plasma of sows G85 and L7(0.05≤P<0.1);Compared with weaned piglets in the CON group,the plasma GSH-Px content of weaned piglets in the APSC group showed an increasing trend(0.05≤P<0.1).5.The effects on immune related cytokines in sows and piglets:Adding APSC to the diet showed a trend of increasing the plasma IL-2 content of sows on the day of delivery(0.05≤P<0.1),and significantly increased the IL-2 content of L7 plasma(P<0.05);Compared with CON group sows,APSC group G85 plasma IFN-γSignificant increase in content(P<0.01),plasma IFN-γon the day of delivery,there is a trend of increasing content(0.05≤P<0.1);In addition,adding APSC to the diet can reduce the plasma IL-6content of sows on the day of delivery(0.05≤P<0.1),and significantly reduce the plasma IL-6 content of L7 and L21 sows(P<0.05);Meanwhile,the plasma TNF-αof G85sows in the APSC group.The content significantly decreased(P<0.01),and the plasma TNF-αof sows on the day of delivery-The content significantly decreased(P<0.05),while the plasma TNF-αof L7 sows.The content also shows a decreasing trend(0.05≤P<0.1);The plasma IL-2 content of weaned piglets fed with APSC showed an increasing trend(0.05≤P<0.1),while plasma IL-6 and TNF levels showed an increasing trend-αThe content significantly decreased(P<0.05).6.Correlation analysis of sow reproductive performance and plasma indicators:There was a highly significant positive correlation(P<0.01)between the loss of back fat during lactation and the 85th day of gestation and delivery of sows(P<0.05).There was a significant positive correlation(P<0.05)between the feed intake of sows in the early(first week),middle(second week),and late(third week)stages of lactation,and a significant negative correlation(P<0.05)between the loss of back fat during lactation.There was a significant negative correlation(P<0.05)between the feed intake during the entire lactation period of sows and the diarrhea rate of piglets in the first week(P<0.05),The feed intake during the second week of lactation was significantly positively correlated with the number of weaned piglets and weaned litter weight(P<0.05).There was a significant positive correlation between plasma antioxidant capacity and inflammatory response in sows at different stages and the body of weaned piglets(P<0.05).Colostrum IgA was associated with plasma IFN-γat G85 of pregnancy in sows there is a significant positive correlation(P<0.05).To sum up,the addition of APSC to the diet of sows during gestation and lactation increased the number of live newborn piglets,significantly reduced the incidence of Stillborn rate and IUGR rate;Simultaneously,significantly increase the feed intake of sows at various stages of lactation and reduce body fat loss during lactation;In addition,the diarrhea rate and mortality rate of lactating piglets were significantly reduced,which increased the number of weaned piglets and the weight of weaned litters;Improve the antioxidant and immune abilities of sows during late pregnancy and lactation,ensuring the health of sows and normal fetal development during gestation. |
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