Supramolecular Functional Materials Constructed By Tetrastyrene Derivatives

As one of the typical molecules that exhibited aggregation-induced emission（AIE）feature,tetraphenylethene（TPE）has been the research focus of scientific researchers due to its unique optical properties scince it was first reported by Tang in 2001.With the development of recent decades,TPE derivatives have emerged in endlessly due to the simple structure,easy synthesis and modification properties.TPE is non-emissive in molecularly dissolved state,but undergo generation or enhancement of fluorescence emission in the aggregated state because of the restriction of intramolecular motions of TPE.It not only solves the limitation caused by the aggregation-caused quenching（ACQ）phenomenon,but also performs incomparable advantages.Due to its unique optical properties,this phenomenon has shown promising applications for photonic devices,fluorescence sensing,bio-imaging and drug delivery.In view of this,the research progress in various fields of diverse derivatives constructed with TPE as the core in recent years is summarized.Then,in the research work,the highly sensitive detection of acidic amino acids by novel fluorescent materials with TPE as the core is described,as well as the application of catalytic synthesis of aminoazoles in medical molecules.It mainly includes the following three chapters:The chapter one,through consulting a large number of literatures on novel fluorescent molecules with TPE as the core,the research progress of different functionalized TPE fluorescent molecular materials in different fields is summarized.For instance,fluorescent sensors based on TPE derivatives can realize the sensing of inorganic molecules and biological molecules.As well as the preparation of polymers with TPE as the AIE fluorophore,and the use of its AIE properties and good biocompatibility to achieve the research of imaging techniques and drug delivery of biological cells.Therefore,the design ideas and research schemes of our program are summarized and proposed.The chapter two,we designed and synthesized a fluorescent molecule TPE-P1consisting of one TPE group with another fluorophore phenazine P1 that can undergo the FRET phenomenon as self-assembly occurring.TPE-P1 self-assembled into microdisks with blue fluorescence emission in THF/H₂O（1:1;v/v）driven by the stack between the TPE groups.Interestingly,these microdisks transformed into microparticles after they were placed in THF/H₂O（1:1;v/v）for 36 hours,and the resultant microparticles show stronger yellow fluorescent emission due to the self-assembled induced F（?）rster resonance energy transfer from TPE groups to phenazine P1 groups.Moreover,these fluorescent microparticles were used for efficient and highly selective detection of L-glutamic acid and L-aspartic acid in THF/H₂O（1:1;v/v）.This work provided a novel and feasible method for the development of materials for the efficient and rapid detection of acidic amino acids.The chapter three,in this part of research work,we explored the catalytic properties of alkyl chain TPE derivatives.We synthesized TPE-4 and TPE-4N,and explored their catalytic synthesis of amino compounds by studying their self-assembled morphology.Following scanning electron microscopy（SEM）,it was found that the derivatives TPE alkyl substituent could form fluorescent nanoparticles,and nanoparticles can rapidly react with tertiary amines to obtain amino compounds under ultraviolet light irradiation.In addition,the obtained amino compound 2NP exhibited favorable acid-base stimulation response behavior.When exposed to acidic conditions,the fluorescence of 2NP was quenched,and exposed to basic conditions the fluorescence was restored.This phenomenon could be repeated for more than 6 times.This work provided a direction for the exploration of new properties of alkyl substituted TPE derivatives,and provided a low-cost,pollution-free AIE photocatalyst for the catalytic field.