The Study On Removal Of Typical Anti-inflammatory Drugs By UV-chlorine And UV-chlorine Dioxide Process

Anti-inflammatory drugs,as a class of commonly used drugs,have attracted extensive attention of researchers for their potential adverse effects on human organs and ecological environment due to the environmental residues produced by their extensive use and their accumulation in the human body and organisms.Carbamazepine（CBZ）is a typical anti-inflammatory drug that has been widely used by humans and animals and frequently detected in the environment.Due to the poor biodegradability of CBZ and the long environmental residual period,this topic intends to use UV/Cl and UV/ClO₂ advanced oxidation processes to carry out in-depth research on the degradation of CBZ,in order to explore a new kind of CBZ with strong oxidative ability under wide p H conditions.The technology provides certain technical guidance for the application of the removal of anti-inflammatory drugs in the future.The basis of comparing the effects of UV direct degradation,oxidant degradation alone,and UV/oxidant combined degradation of CBZ,the paper systematically studied the factors affecting the degradation of CBZ in UV/Cl reaction system and UV/ClO₂reaction system,and discussed the oxidant（HClO,ClO₂）dosage,solution p H,coexisting ions（chloride and bicarbonate ions）and other factors on the degradation of CBZ.The results showed that when the dosage of oxidant was doubled（from 30μmol/L to 60μmol/L）,the degrading ability of UV/Cl system and UV/ClO₂ system could be increased by 1.39 times and 1.41 times,respectively;the change of environmental p H The ability of UV/Cl system to degrade CBZ has a great influence,and the lower p H value（p H=6）is beneficial to the degradation of CBZ,but the UV/ClO₂ system is not greatly affected by p H;the coexistence of HCO₃^-ions degrades the two systems CBZ has a great inhibitory effect,while the coexistence of Cl^-ions only has a significant inhibitory effect on the degradation of CBZ in the UV/ClO₂ system,and has little effect on the UV/Cl system.The kinetic studies of CBZ degradation by UV/Cl system and UV/ClO₂ system showed that the kinetic models of CBZ degradation in both systems were well fitted with the first-order kinetic model,and it was speculated that it was a pseudo-first-order reaction.The reaction rate constants under different oxidant dosages were calculated.The paper analyzed and calculated the free radical contribution of UV/Cl system and UV/ClO₂ system to degrade CBZ.The calculation results showed that the RCS had the highest contribution to the degradation of CBZ under the two systems.In the UV/Cl system,·OH is second,and the contribution of UV direct photolysis is the lowest;in the UV/ClO₂ system,the contribution of UV direct photolysis is second,and the contribution of·OH is the lowest.In addition,for the UV/Cl system,as the reaction progresses,the contribution of RCS tends to decrease,and this part of the reduced contribution is converted into an increase in the contribution of OH.At the end of the paper,the degradation products of CBZ degraded by UV/Cl system and UV/ClO₂ system were systematically analyzed and the degradation paths were reasonably speculated.The results showed that CBZ was not completely degraded in both systems,and some intermediates were not degraded into small molecular carbon chains.In addition,it was found that in the UV/Cl system,the degradation products contained chlorinated organic compounds,and these intermediates were important for The negative impact of environmental ecology remains to be studied.