Evaluation Of Antibacterial Effects Of Two-dimensional Nanomaterials MXen And Complexes

Nanomaterials are the current research frontier in the field of materials.The research and application of nanomaterials have brought subversive technological revolutions to many basic fields.2D nanomaterials are an important part of the field of nanomaterials.It has been found that 2D nanomaterials have unique structures and many excellent properties,and can be widely used in many fields.Countries around the world invest a lot of manpower and material resources in research,development and application,triggering a global technological revolution and forming new breakthroughs.The antibacterial properties of 2D nanomaterials have been widely studied and reported in recent years.The current research on 2D nanomaterials represented by graphene and MXene has a good development prospect in the field of antibacterial.There are many researches on the antibacterial properties and mechanisms of 2D nanomaterials at home and abroad,but the systematic evaluation of the application of2D nanomaterials,the horizontal comparison of the antibacterial conditions and mechanisms of various 2D nanomaterials,and the transformation and application of 2D nanomaterials are still in progress.It is not deep enough.In order to solve the above scientific problems,based on the evaluation of actual antibacterial properties of nanometer antibacterial fabrics in the domestic market,this paper evaluates the preparation of two MXene materials and their Ag nanoparticle-loaded composites,and the physical characterization,antibacterial properties and antibacterial mechanism were analyzed systematically for the future applications.The first part:collect the fabrics with nano antibacterial properties that are currently sold in the domestic market,evaluate theirs antibacterial properties,and select three fabrics with better antibacterial rates by comparison.The three excellent fabrics were analyzed,and the microscopic observation of the antibacterial situation was carried out by scanning and transmission electron microscopy.Finally,compare the common 2D nanomaterials:graphene（GO）,black phosphorus（BP）,titanium carbide（Ti₃C₂）and niobium carbide（Nb₂C）,and compare their antibacterial abilities.It is found that Ti₃C₂and Nb₂C have better antibacterial properties than GO and BP in MXene materials,and have the potential to become antibacterial materials.Therefore,they can be used as candidate materials for 2D nano-bacteriostatic materials,which lays a theoretical foundation for the next research on Ti₃C₂and Nb₂C nanomaterials.The second part:Ti₃C₂was successfully prepared by selective etching of Ti₃Al C₂and organic alkali intercalation,Ti₃C₂-Ag complex was prepared by adding silver ammonia solution,and the physical characterization and physical stability of the preparation were analyzed.Detect their antibacterial activities by short-term,long-term fixed concentrations and different times,and found that Ti₃C₂and Ti₃C₂-Ag have high antibacterial activities.Finally,the antibacterial mechanism of Ti₃C₂-Ag complex was studied and analyzed in depth,and it was found that its antibacterial mechanisms include（1）physical cleavage;（2）induction of cell disruption;（3）stimulation of oxidative stress and other mechanisms.And this part laid a theoretical basis for later research on the properties of Ti₃C₂and Ti₃C₂-Ag complex.The third part:2D nanomaterial Nb₂C was prepared by selective etching of Nb₂Al C.Nb₂C-Ag complex was prepared by adding silver ammonia solution.It is proved that Nb₂C and Nb₂C-Ag complex have clear two-dimensional morphology by the microscopy.The elemental composition of Nb₂C and Nb₂C-Ag complex was analyzed by spectroscopy to verify the specific elemental composition.To better understand the antibacterial properties of Nb₂C and Nb₂C-Ag complex,the antibacterial activities of Nb₂C and Nb₂C-Ag complex against Escherichia coli（E.coli）and Staphylococcus aureus（S.aureus）were studied in different layers,short-term,long-term,fixed concentrations and different times.Finally,the antibacterial properties of these 2D nanomaterials were determined by studying the antibacterial mechanism of Nb₂C and Nb₂C-Ag complex.Antibacterial activity studies have enriched the understanding of the antibacterial activities of the MXene family.In summary,this study evaluated the properties of 2D nanomaterials in practical applications comprehensively and systematically,prepared two nano-antibacterial composites successfully with high antibacterial efficiency,and analyzed its antibacterial properties and mechanism systematically which provided theoretical and practical experience for the later researcher on the preparation of nano antibacterial materials.