Simulation Of Action Potential Release Charactristics Of Several Different Types Of Neurons

Action potentials are signals that the brain receives,analyses and transmits information with all-or-nothing and attenuation-free transmission,and are transmitted through neurons.Different neurons transmit different information,and the action potentials transmitted to visual,tactile and olfactory cortices which carry different messages.Action potentials delivered by neurons have received a great deal of attentions from researchers because of their important role in cortical function,however,the delivery of action potentials by various neurons in response to different current stimuli has not been well studied.In this paper,the Izhikevich spiking neuron model is used to simulate the firing of action potentials from several neurons under different types of current stimulation.By observing the changes in the delay time and frequency of action potentials,we investigated the characteristics of action potentials delivered by different types of neurons.In this paper,simulates the firing of action potentials when two types of excitatory neurons(regular pulse neurons and intrinsically clustered pulse neurons)are stimulated with different types of currents.The effect of the variation of the input current on the firing of action potentials was analysed when the stimulation currents were DC,step current,rectangular pulse current,square wave current and sinusoidal current respectively.The pattern of action potential delivery was revealed when the frequency of the square wave and sinusoidal currents were varied.The differences between the two types of excitatory neurons in terms of the action potentials delivered by different current stimuli were also compared.The effects of resting membrane potential and membrane recovery variables on the action potential delivery pattern of neurons were investigated using regular pulse neurons as an example.In this paper,simulates the action potential firing characteristics of two inhibitory neurons(fast pulse neurons and low threshold pulse neurons)when stimulated by different types of currents.The type,intensity and frequency of the stimulation currents were varied to observe the firing of action potentials from the neurons,and the firing characteristics of the action potentials from the two inhibitory neurons were compared under different stimulation current variations.The pattern of action potential emission from the two inhibitory neurons under different types of current stimulation is described.The simulation results showed that the greater the current intensity,the greater the frequency of action potential firing and the shorter the hesitation time.When the frequency of the square and sinusoidal currents was increased,more clusters of action potentials were delivered and the frequency of action potentials delivered in each cluster decreased.When stimulated with rectangular pulse currents,the wider the pulse width and the greater the time interval between rectangular pulses,the easier it is for the neuron to deliver action potentials;inhibitory neurons are more likely to give out action potentials relative to excitatory neurons.