| Objective:the main purpose of this study is to summarize the ancient literature and application of the prescription of Maimendong decoction,and to determine the common flavor and frequency of the combination prescription by analyzing the clinical data,and to analyze and discuss the common changes of the follow-up prescriptions and the rules of the prescriptions used after the use of the medicine.The symptom and the follow-up pathological mechanism of meimendong Decoction were summarized.Methods:the clinical cases of respiratory experts in Dongzhimen Hospital of Beijing were collected in 8 years and.8 years.From these cases,70 patients taking Maimendong Decoction were selected and all the information was collected and analyzed,including age,traditional Chinese medicine diagnosis,western medicine diagnosis,symptoms,phlegm,tongue and pulse,formula,combined prescription and subsequent changes.The ratio of respiratory diseases was calculated in this study,which indicated the most common increase and decrease of Maimendong Decoction and the most common follow-up syndrome changes after taking Maimendong decoction.Results:in the analysis of the basic data,clinical symptoms,diagnosis of traditional Chinese and western medicine,drug addition and subtraction,combination prescription addition and subtraction,and subsequent prescription changes of 70 patients in this study,it was found that 46 patients were female(65.71%),slightly larger than 24 men(34.29%).In terms of age,the majority of patients were 51-60 years old and 61-70 years old.12(17.14%)and 21(30%)persons,respectively.There were 50 clinical symptoms,a total of 293 times.The frequency of the top 10 for cough(17.41%)dry mouth(11.60%)expectoration(10.92%)pharynx itching(8.87%)o(3.41%)shortness of breath(3.07%),pharynx foreign body sensation(3.07%),insomnia(3.07%),fatigue(2.73%),bad asthma(2.73%),pharynx(2.73%),while the tongue like a tongue(35.87%)with dark red tongue red tongue(14.13%)dark tongue(11.96%)tongue(11.96%)of crack,reddish tongue(10.87%),moss as to thin white moss(53.42%),thin yellow moss(23.29%),and greasy moss(12.33%).The pulse features were mainly thin string(38.75%),string slip(18.75%),thin slip(13.75%)and deep vein(8.75%).Of sputum like to white sputum(63.16%),phlegm(73.08%),less(54.17%)or no sputum(33.33%).In terms of TCM names,cough(37.14%),lung impotence(24.29%),meiheqi(8.57%),exhaustion(7.14%)and internal fever(5.71%)were the most common names,while interstitial lung disease(27.14%),chronic cough(24.29%)and chronic bronchitis(15.71%)were the most common names in western medicine.In addition,lung diseases are the main diseases in both traditional Chinese and western medicine.In terms of addition and subtraction there were a total of 62 flavors.In addition to the original medicinal flavor of Maimondon Decoction,there were burdock seed(48.57%),angelica(40.00%),radix scutellariae(30.00%),white mulberry root-bark(28.57%),and the bone skin(27.14%),the presence of the plaster stone(22.86%),the highest frequency.There were 13 kinds of combined formulas,8 cases of Huangqin Xiebai Powder(22.22%),7 cases of Xiebai Powder(19.44%),and 5 cases of Zhuye Geshu Decoction(13.89%)had the highest frequency.Among the 70 patients who took Madondon Decoction,60 cases(85.71%)were effective and 10 cases(14.29%)were ineffective,among which 26 cases(37.14%)were effective subsequent variants.There were 2 cases(7.69%)of small chaihu decoction combined with Banchia Magnolia decoction,2 cases(7.69%)of small chaihu decoction combined with Weijing decoction,2 cases(7.69%)of small chaihu decoction combined with Wendan decoction,1 case(3.85%)of small chaihu decoction combined with Gegen decoction,1 case(3.85%)of small chaihu decoction combined with small qinglong plus geshu decoction,1 case(3.85%)of small chaihu decoction combined with big chaihu decoction combined with hegui Zhi Fu Ling pill 2 cases(7.69%),Maxing Shi Gan decoction 1 case(3.85%),Guizhi plus Houpu Xing Zi decoction 1 case(3.85%),Chaihugui Zhi Gan Jiang decoction 2 cases(7.69%),Banxia Xiexin decoction 1 case(3.85%),Guahanqumai pill and Zhu Ling decoction 1 case(3.85%),Wumei pill 1 case(3.85%),Danzhi Xiaoyao powder 1 case(3.85%)85%),1 case of Jiuwei Qianghuo decoction(3.85%),1 case of Buzhong Yiqi Decoction and Erzhi Wan(3.85%),1 case of Kong Sheng Zhizhongdan(3.85%),2 cases of Maimendon decoction combined with Gardenia Soy Decoction(7.69%),1 case of Maimendon decoction combined with Fengmedan(3.85%),1 case of Maimendon decoction combined with Shengma Biejia Decoction(3.85%).Among them,15 cases(57.69%)were Bupleurum type,12 cases(46.15%)were Pinellia-type,7 cases(26.92%)were Guizhizi type,5 cases(19.23%)were dried ginger type,4 cases(15.38%)were non-traditional decoction,and 4 cases(15.38%)were Maimondon decoction combination syndrome.According to the statistics,the most common subsequent change of prescription of Maimendon decoction was Xiaobaihu decoction,of which Xiaobaihu decoction alone accounted for 11.11%,Pinelaria magnolia decoction,Wendan decoction and Weijing decoction accounted for 22.22%,22.22%and 22.22%respectively,and Puergen decoction and Xiaoqinglong plus gesso accounted for only 11.11%and 11.11%.The second most common formula of Maimendon decoction was Dachaihu decoction and Chaihu-gui branch and ginger decoction.Conclusion:1.Maimendong decoction has good therapeutic effect on the western medicine diseases such as chronic cough,chronic bronchitis,interstitial lung disease,pulmonary fibrosis,chronic pharyngitis and other pulmonary diseases.2.Combined with the experience of medical practitioners and the study of medical records,the symptoms,tongue pulse and phlegm of Maimendong decoction can be supplemented.It can provide more practical reference for Zhang Zhongjing in the brief description of the original version of Maimendong decoction.The symptoms can be roughly classified as the symptoms of fire and upward Qi,throat disadvantage,and systemic performance."The fire can be counter to the Qi can be added:"asthma,cough,runny,vomiting,coughing blood cough saliva and other symptoms." "Throat is not good can be added:"dry throat,itching,pain,difficult to eat,phlegm sound not wet and other symptoms."The whole body performance can be added:"fever,hand and foot irritating heat,sweating,thirst and other symptoms." Tongue image can be added:"dark red tongue,dim tongue,cracked tongue light red tongue,etc." Pulse image can be added:"pulse number,pulse fine string,pulse string slip,pulse thin slip,pulse sink,etc." Phlegm image can be added:"phlegm white mucus,less or no phlegm." The above summary can be used as a reference for modern clinical practice of Maimendong decoction.3.The combination of single flavor medicine and combined prescription can be summarized from the literature of previous dynasties,such as adding Gallic to phlegm and relieving cough,adding gypsum to stop cough blood,and smallpox powder to treat thirst,body heat and asthma.Add gypsum and bamboo leaves to stop nausea and reduce fire.Go to Banxia and North ginseng to treat lung vein injury,blood accumulation and other syndromes.In the experience of the tutor,Danggui was used to strengthen the treatment of cough and upward Qi,and burdock and yam were added to make the spleen and lung run and down the counter Qi.He xiebishan was used to clear heat and reduce the adverse gas,and baicalin was added to clear lung heat and Shaoyang depression.He chaipu Tang is hot with Shaoyang in Qing Dynasty and drinks in Taiyin.He Qingzao Jiufei decoction is used to declare the external feeling of warm and dry evil.He acid Zaoren Decoction to treat Yang Ming deficiency heat insomnia.He Zhizi Douchi Decoction to treat Yang Ming Depression Insomnia,and heartburn,or cough.4.From the six classics syndrome differentiation,the syndrome of Maimendong Decoction belongs to Yang Ming deficiency heat syndrome,in the follow-up change formula,Chaihu is half surface and half Li Shaoyang syndrome,suggesting that after treatment,the disease has a tendency to change to half surface and half Liyang syndrome.After the treatment of Maimendong decoction,the stomach body is still empty,and the function of transportation is not fully restored,the upper and lower axis opening and closing of Taiyang Ming can be strengthened.The appearance of Guizhi prescription is partly due to the middle-term external feeling,which is not the normal pathological mechanism of the follow-up of the syndrome of mcmurdong decoction.In addition,after the diseases of Taiyang and Ming are recovered,the effect of adjusting Ying Wei to strengthen the sun and keeping the health can prevent the evil Qi from being repeated.After treatment of Maimendong decoction,if the dry ginger prescription is treated with the treatment of the medicine,if the phlegm syndrome is caused by the excessive clean and moist,the syndrome of phlegm with anti cold syndrome or the external feeling in the middle of the course,if the Yin subdues the drink,it can be put into operation to recover the stomach Yang and go out with evil spirits.In conclusion,it provides reference for the general rule and modern application of Maimendong decoction. |
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