Clinical Observation Of Shenzao Ningxin Decoction In The Treatment Of Chronic Heart Failure Complicated With Insomnia (Qi-yin Deficiency Syndrome)

Objective:By observing the clinical efficacy of Shenzao Ningxin Decoction in the treatment of patients with chronic heart failure(CHF)combined with insomnia due to deficiency of both qi and yin,it provides a reference for the treatment of heart failure.Methods: Sixty patients meeting the inclusion criteria were randomly selected and randomly divided into two groups,the test group and the control group,with 30 cases in each group.The control group was treated with conventional Western medicine for anti-heart failure,and the test group was treated with Shenzao Ningxin Decoction(Ginseng,Ophiopogon,Schisandra,Suanzaoren,etc.)on the basis of the control group.4 weeks was a course of treatment.Results:Before treatment,there was no statistical difference between the two groups in terms of age,gender,course of disease,comorbid diseases,and cardiac function classification.(1)Comparing the curative effect of heart failure and heart function,the effective rate of Shenzao Ningxin Decoction group was 83.3%,and that of control group was 60.0%,the difference was statistically significant(P<0.05);(2)Compared with NT-pro BNP,the NT-pro BNP of Shenzao Ningxin Decoction group and the control group were significantly decreased,the difference was statistically significant,but the comparison between the groups,the efficacy of Shenzao Ningxin Decoction group and the experimental group was not statistically significant;(3)Comparing the TCM syndrome scores,the TCM syndrome scores of the Shenzao Ningxin Decoction group decreased from 15.73±2.82 before treatment to 10.23±2.06 after treatment,the difference was statistically significant(P<0.01),and the control group scores were not seen obvious change;(4)Compared with the Pittsburgh Sleep Index(PQSI)score,the PQSI score of the Shenzao Ningxin Decoction group decreased significantly,and the difference was statistically significant(P<0.05).The PQSI score of the control group also decreased slightly,but the difference was not statistically significant(P >0.05),the therapeutic effect of Shenzao Ningxin Decoction group on sleep quality was significantly better than that of the control group;(5)Comparing on the Minnesota Quality of Life Scale,the scores of the Shenzao Ningxin Decoction group and the control group on the Minnesota Quality of Life Scale decreased slightly,and there was no statistical difference between the two groups before and after treatment.Conclusion: This study shows that Shenzao Ningxin Decoction has better efficacy than conventional Western medicine in terms of sleep quality,TCM syndromes,and clinical symptoms,and has fewer clinical adverse reactions.It is worthy of further clinical application and research.