An Appliction Study Of Cerebral Visual Training In Glaucoma Patients With Visual Function And Visual Field Impairment

Objective:Virtual reality technology is used to provide plasticized cerebral visual training to primary glaucoma patients with visual function and visual field impairment,with the aim of improving the visual quality and quality of life of patients.Methods:A prospective study was conducted of seventy-two patients with primary glaucoma who received cerebral visual training in the department of ophthalmology of Sichuan Provincial People’s Hospital from May 2020 to October 2021,and followed up for 3 months to observe the changes in visual function and visual field at 1 month,2 and 3 months after training,and the improvement of visual quality and quality of life of glaucoma subjects were comprehensively assessed by relevant questionnaire scores.The main observation indexes included visual acuity,intraocular pressure,horizontal and vertical perceptual eye position,gaze stability,suppression,stereopsis,visual noise,mean deviation（MD）,pattern standard deviation（PSD）,the completion of the visual function questionnaire（NEI-VFQ-25）and glaucoma quality of life questionnaire（GQL-15）.Results:Fifty-eight patients with primary glaucoma were included in the final statistical analysis.There was no statistical difference in the changes of visual acuity,intraocular pressure and the number of IOP-lowering drops in the patients after receiving cerebral visual training（P=0.67>0.05）;compared with the pre-training baseline data,the differences in perceptual eye position,gaze stability,suppression,stereopsis,and visual noise were statistically significant（χ~2=34.483,χ~2=110.825,χ~2=125.005,χ~2=135.968,χ~2=177.931,all P<0.005）;visual field impairment improved to some extent after receiving cerebral visual training,and there was a positive correlation between the duration of training and the efficiency of visual field improvement（r=0.969）,but MD and PSD were not statistically different compared with those before training（both P>0.05）.NEI-VFQ-25 and GQL-15 questionnaires showed that the visual quality and quality of life of glaucoma patients improved with statistical differences（both P<0.05）after cerebral visual training.Conclusion:For primary glaucoma patients with visual function and visual field impairment,cerebral visual training based on virtual reality technology can be effective in improving visual function and visual field to varying degrees,improving the visual quality and quality of life,whether it can be applied to the treatment and follow-up of glaucoma patients in clinical practice needs to be supported by data from large samples and long-term follow-up studies.