| Purpose:The perioperative and postoperative complications and functional recovery of double kidney transplantation（DKT）were observed with expanded standard donor single kidney transplantation（ecdskt）as control.Method:In this study,in order to retrospectively analyze 17 cases of DKT surgery performed in the second Department of Urology,Bethune first hospital,Jilin University from January 1,2020 to December 31,2021,and then select the clinical data of 17 cases of ecdskt surgery performed in the same period as the control,the recipients were divided into DKT recipient group and ecdskt recipient group according to the comprehensive situation of the donors,The incidence of perioperative and postoperative complications（bleeding,acute rejection（AR）,delayed graft recovery（DGF）infection,death）,renal allograft function at discharge and survival rate of transplanted kidney and patients,recent renal allograft function and survival rate of transplanted kidney and patients were compared.The perioperative and postoperative complications（bleeding,AR,DGF,infection,death）,the renal function and survival rate of the recipients at discharge,the recent renal function and survival rate of the recipients were observed;The differences between the two groups were analyzed.Results:The average follow-up time of the recipients in DKT group and ecdskt group was（8.88 ± 6.34）months.Except for the difference in the quality of the donor kidney,the recipients in both groups were operated at the same time,and their basic conditions were basically the same;In the DKT group,there were 1 case of postoperative complications（1 case of fever,1 case of diarrhea,1 case of urinary tract infection,2 cases of BK virus infection,8 cases of ar8,4 cases of dgf4,and 1 case of renal allograft hemorrhage）,in which 1 case of renal allograft hemorrhage resulted in renal allograft failure and patient death.In the ecdskt group,there were 4 types of postoperative complications（8 cases of dgf8,1 case of interstitial lung infection,1 case of urinary tract infection,3 cases of Ar3,and 1 case of renal allograft hemorrhage）,in which 1 case of renal allograft failure resulted from renal allograft hemorrhage.The average creatinine of DKT group was（166.96 ± 75.95）/umol/l at discharge,and that of ecdskt group was（148.23 ± 84.70）/umol/l at discharge.The graft survival rate and patient survival rate were 100% in DKT group,and 94.11% in DKT group;The graft survival rate and patient survival rate in ecdskt group were 100% at discharge.The recent graft survival rate in ecdskt group was 94.11% and the patient survival rate was100%.Conclusion:Double kidney transplantation does not increase the type and number of complications,and DKT is safe and reliable.Although the quality of single kidney of DKT donor kidney is worse than that of single kidney of ecdskt donor kidney,when both kidneys are given to one recipient at the same time,the follow-up results of renal function of recipients in ecdskt group and DKT group are compared.From the paired t-test results,the double p value is 0.1846,which is not statistically significant,indicating that there is no significant difference in the recovery of renal function between DKT group and ecdskt group.The selection of DKT donors in the center,combined with the remuzzi score,and with reference to the comprehensive evaluation of the comprehensive score（history,pre acquisition creatinine,CRP time and times,LP,age,BMI,glomerular sclerosis rate）,will become an effective potential supplement to the future marginal donor kidney,and a new source Bank of organ transplantation kidney.In the long term,compared with the ecdskt group,the average follow-up time at this stage is（8.88 ± 6.34）months.The follow-up time needs to be further increased,and the number of DKT recipients also needs to be increased.It is best to provide multi center large sample research.We also need further observation to obtain more accurate data,so as to draw a more scientific standard. |
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