Clinical Study Of Low-frequency Ultrasonic Neuromuscular Electrical Stimulation In Posterior Circulation Ischemic Vertigo

ObjectiveThe clinical efficacy of low-frequency ultrasound neuromuscular electrical stimulation in patients with posterior circulation ischemic vertigo（PCIV）was initially evaluated by observing patients with posterior circulation ischemic vertigo,and its possible mechanism of action was explored to provide a basis for the clinical application of low-frequency ultrasound neuromuscular electrical stimulation.MethodsOne hundred and five patients with posterior circulation ischemic vertigo（PCIV）who were hospitalized in the neurology department of a hospital from September 2020 to October 2021 were selected.They randomly divided into experimental or control group after signing the informed consent.According to the exclusion criteria and shedding criteria,98 cases of patients were collected,randomized to 49 people in the experimental group and 49 people in the control group,respectively.The control group was treated with conventional medication: 0.9% sodium chloride injection250ml+Guhong injection 20 ml ivgtt qd.The experimental group was additionally given low-frequency ultrasonic neuromuscular electrical stimulation treatment on the basis of the control group.For the underlying diseases such as hypertension,diabetes mellitus and hyperlipidemia,corresponding pharmacological interventions were performed according to the "Chinese Guidelines for Secondary Prevention of Ischemic Stroke and Transient Ischemic Attack" [1].Patients in both groups were treated for 7 days.The visual analog scale（VAS）score,dizziness impairment scale（DHI）score and circulatory hemodynamic changes after transcranial Doppler ultrasound（TCD）were observed and recorded before and after treatment in both groups for assessing the treatment effect.Data entry was performed using Epi Data 3.0 software and SPSS 26.0software for data analysis.Results1.Comparison of clinical efficacy: Both groups were effective in improving posterior circulation ischemic vertigo,the total effective rate of the experimental group was 87.8%,and the total effective rate of the control group was 73.5%.The clinical treatment effect of the experimental group was better than that of the control group,the difference was statistically significant（P<0.05）.2.Comparison of visual analog scale（VAS）scores: The VAS scores of patients in both groups decreased to different degrees compared with those before treatment,and the difference was statistically significant（P<0.01）;the difference was statistically significant（P<0.05）when compared between the two groups after treatment.3.Comparison of Dizziness Impairment Inventory（DHI）scores: The DHI scores of both groups decreased to different degrees compared with those before treatment,and the difference was statistically significant（P<0.01）;after treatment,the difference between the two groups was statistically significant（P<0.01）.4.Comparison of transcranial Doppler ultrasound（TCD）flow parameters: The mean flow velocity（Vm）of vertebral artery and basilar artery improved to different degrees compared with that before treatment in both groups.The difference was statistically significant（P<0.05）when comparing the two groups after treatment.P<0.05).5.Safety: There were no obvious adverse reaction in the treatment process in both groups.Conclusion1.Low-frequency ultrasound neuromuscular electrical stimulation combined with conventional drug treatment can effectively relieve the symptoms of posterior circulation ischemic vertigo.And it is better than conventional drug treatment group in improving VAS score and DHI score.The clinical efficacy is obvious.2.Low-frequency ultrasound neuromuscular electrical stimulation can effectively improve the mean blood flow velocity of basilar artery（BA）and bilateral vertebral artery（VA）,and the degree of improvement is better than that of conventional drug treatment.3.Low-frequency ultrasound neuromuscular electrical stimulation was not found to have significant adverse effects during clinical application.It is simple,easy to use,safe and non-invasive,and can be clinically promoted as a treatment method for PCIV.