| Objective: To investigate the clinical value of CT guided autologous blood and micro-coil localization in accurate resection of pulmonary ground glass nodules before thoracoscopic surgery.Methods: We retrospectively reviewed the clinical data of patients who underwent thoracoscopic lung ground glass nodule resection by preoperative CT guided autologous blood(34 patients)and micro-coil(31 patients)localization in the department of cardiothoracic surgery in our hospital from September 2018 to September 2020,the two localization methods were compared in terms of cost,localization time,time to lobectomy wedge resection,localization success rate,lung wedge resection rate,localization complication rate,and transthoracic thoracotomy rate.Result: A total of 65 ground glass nodules in the lung of 65 patients were completed by the two localization methods,including 34 cases in the autologous blood localization group and 31 cases in the micro-coil localization group.There was no significant difference between the two groups in terms of gender,age,nodule size,nodule location,and distance of the nodule from the pleura.The localization cost of the autologous blood localization group was lower than that of the micro-coil localization group(585(585,585)yuan in the autologous blood localization group,3025(3025,3025)yuan in the micro-coil localization group),with statistical significance(P<0.001).The localization time of autologous blood localization group was shorter than that of micro-coil localization group(autologous blood localization group(14.56±2.25 min,micro-coil localization group(16.29±2.74 min)),the difference was statistically significant(P=0.007).The localization success rate of the autologous blood localization group was higher than that of the micro-coil group(32 successful locations in the autologous blood localization group(94.1%),26 successful locations in the micro-coil localization group(83.9%)),and the difference was not statistically significant(P=0.183).The incidence of puncture complications in the autologous blood localization group was lower than that in the micro-coil localization group(1 case of small pneumothorax in the autologous blood localization group(2.9%),the micro-coil localization group occurred 4 cases of small pneumothorax(12.9%),1 case of small pulmonary hemorrhage(3.2%),1 case of hemoptysis(3.2%)and 1 case of mild pleural reaction),and the difference was not statistically significant(P=0.192).The time of wedge resection in the autologous blood localization group was longer than that in the micro-coil localization group(autologous blood localization group(22.59±3.32min),micro-coil localization group(16.94±3.72 min)),the difference was statistically significant(P<0.001).The wedge resection rate in the autologous localization group was lower than that in the micro-coil localization group(29wedge resection sites(85.3%)in the autologous localization group,and 28 wedge resection sites(90.3%)in the micro-coil localization group),with no statistically significant difference(P=0.538).No patients in the two groups were converted to thoracotomy.Conclusion: Autologous blood localization and micro-coil localization are good preoperative pulmonary nodules localization methods,compared with micro-coil localization,The autologous blood group had lower localization time and cost,a higher success rate of localization,the puncture complications and wedge resection rates has no statistical significance.Autologous blood localization is economical,safe,effective,and easy to perform as a good method for preoperative lung nodule localization and deserves clinical promotion. |