| Objective:To explore the effect of intervention of phase Ⅰ cardiac rehabilitation(P Ⅰ CR)on cardiac function,exercise tolerance and quality of life of patients with acute myocardial infarction(AMI)after percutaneous coronary intervention(PCI),to provide evidence for the timing and effectiveness of P Ⅰ CR intervention,to promote the development of P Ⅰ CR,and to benefit AMI patients after PCI.Methods:From January 2020 to December 2020,Of the 90 patients who met the criteria for admission to the study and who voluntarily accepted the study with informed consent were first diagnosed with AMI and successfully underwent PCI surgery,Depending on the treatment plan,Patients were randomly divided into three groups:control group(n=30),P Ⅰ CR group(n=30)and P Ⅱ CR group(n=30),To collect the clinical data of age,sex,systolic blood pressure(SBP),diastolic blood pressure(DBP),smoking history,hypertension history,diabetes history,height,weight,cardiac function grade,myocardial infarction site,coronary angiography results such as vascular disease,stent and drug treatment,To collect abdominal blood sugar(FBG),total cholesterol(CHOL),triglyceride(TG),high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C),laboratory indicators such as brain natriuretic peptide(BNP),creatine kinase isoenzyme B(CK-MB),cardiac troponin I(cTnI)at admission and discharge;The cardiac output(CO),stroke output(SV),ejection fraction at admission,1 month postoperatively and 3 months postoperatively(LVEF),of 6 minutes walking test distance(6MWD),cardiopulmonary exercise test data and SF-36 quality of life score data for 1 month and 3 months after discharge.Results:1.Comparison of myocardial injury markers:There was no significant difference in CK-MB、c-TnI between the three groups(P>0.05).The CK-MB、c-TnI of the three groups decreased significantly at the time of discharge,and there was no significant difference between the three groups(P>0.05).2.Comparison of cardiac function indicators:There was no significant difference in LVEF、BNP between the groups at admission(P>0.05).At the time of discharge,the BNP values of the three groups decreased significantly,And there was no significant difference between the groups(P>0.05).There was no significant difference in the LVEF value of the control group at 1 month and 3 months after PCI operation(P>0.05).After 1 month,the LVEF of P Ⅰ CR group was significantly higher than that of control group,difference was statistically significant(P<0.05);(a)There was no significant difference between P Ⅰ CR group and PIICR group(P>0.05);Three months after surgery,LVEF value of PⅠ CR group was higher than that of PIICR group and control group,difference was statistically significant(P<0.05).There was no significant difference in the CO、SV value of each group on the day after operation(P>0.05).The CO、SV value of P Ⅰ CR group was significantly increased(P<0.05);The 6-minute walking test distance(6MWD)in P Ⅰ CR group was significantly better than that in control group and PIICR group(P<0.05).3.Comparison of cardiopulmonary exercise test indicators:One month after surgery,three months after surgery,the VO2max/kg、AT time VO2/kg and AT time were compared,P Ⅰ CR group was significantly higher than the other two groups,difference was statistically significant(P<0.05).4.Comparison of SF-36 quality of life scores:There was no significant difference in PF、RP、BP、GH、VT、SF、RE、MH 8 dimension scores between the three groups(P>0.05);One month after surgery,P Ⅰ CR group improved significantly in PF、RP、BP、VT、SF、RE6 dimensions,The scores were higher than those of the control group,difference was statistically significant(P<0.05).Three months after surgery,P Ⅰ CR group improved significantly in 8 dimensions,difference was statistically significant(P<0.05);And compared with PIICR,A marked improvement in all dimensions except MH,difference was statistically significant(P<0.05);and the control group improved only in PF、RP、RE、VT4 dimensions.Conclusions:AMI early phase Ⅰ cardiac rehabilitation is safe and feasible for patients undergoing PCI treatment,and is beneficial to the recovery of cardiac function,the improvement of exercise tolerance and the improvement of quality of life. |
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