| ObjectiveTo explore the effects of aerobic exercise combined with cognitive behavioral therapy(CBT)on cancer-related fatigue(CRF),quality of life(QOL),anxiety,depression and radiation dermatitis in breast cancer patients undergoing radiotherapy,so as to provide the ideas and basis for related nursing measures.MethodsIn this study,we use quasi-experimental research methods.A total of 62 women with CRF treated for breast cancer in radiotherapy wards of a third grade A hospital in Inner Mongolia were selected by convenient sampling method.Women in control group received aerobic exercise on usual care according to the guidelines,and women in intervention group received aerobic exercise combined with Cognitive Behavioral Therapy(CBT).The intervention lasted for 6 weeks.The Revised Piper Fatigue Scale—Chinese Version(RPFS-CV),The Functiond Assessment of Cancer Therapy-Breast(FACT-B),The Self-Rating Anxiety Scale(SAS)as well as the Self-rating Depression Scale(SDS)and radiation dermatitis scoring criteria were used to score before intervention,at the 3rd week and at the 6th week of intervention to analyze the intervention effect.Results1.Finally,there are 62 effective cases,including 31 cases in the control group and31 cases in the experimental group.2.General data comparison: Both groups before intervention in marital status,education level,occupation,religious beliefs,family per capita income,payment method,medical diagnosis,tumor stage and menopause has no statistical difference(P > 0.05).two groups of data are comparable.3.Before intervention,there were no statistical differences in CRF,quality of life,anxiety,depression and radiation dermatitis between the two groups(P > 0.05),and the data were balanced and comparable.4.Effect of intervention on CRF:Results of repeated measures analysis of variance: The intervention effects in total score,severity dimension score and cognitive/mood dimension score were statistically significant between the two groups(P<0.05).The time effects of total score and scores of all dimension were statistically significant(P<0.05).Total score and scores of all dimension had an interactive effect(P<0.05).Comparison of results between groups: After 3 weeks of intervention,the cognitive/mood dimension scores of the two groups were statistically significant(P<0.05).After 6 weeks of intervention,the total score and scores of various dimensions in the two groups were statistically significant(P<0.05).Comparison of results in group: the scores of affective meaning dimension,sensory dimension and cognitive/mood dimension at three time points in the control group were statistically significant(P<0.05);The total score and the scores of each dimension at 3time points in the experimental group were statistically significant(P<0.05).5.Effect of intervention on quality of life:Results of repeated measures analysis of variance: The intervention effects of the intervention on the total score,social and family well-beings and functional well-beings were statistically significant between the two groups(P<0.05).The time effect of the total score and the scores of each dimension was statistically significant(P<0.05);The interaction effect of the total score and the scores of each dimension was significant(P<0.05).Comparison of results between groups: After 3 weeks of intervention,the total score and the dimension scores of additional concerns were statistically significant(P<0.05);After 6 weeks of intervention,with the exception of physical well-being all results were statistically significant(P<0.05).Comparison of the results in group: With the exception of the functional well-beings all results in the control group at three time points were statistically significant(P<0.05);The total score and the scores of each dimension at three time points in the experimental group were statistically significant(P<0.05).6.Effect of intervention on anxiety and depression:Results of repeated measures analysis of variance: There was no significant difference in intervention effects between the two groups(P>0.05).The time effects of the scores between the two groups were statistically significant(P<0.05).Anxiety and depression scores had interaction effects(P<0.05).Comparison of results between groups: After 3 weeks of intervention,the scores between the two groups were not statistically significant(P>0.05).After 6 weeks of intervention,the scores between the two groups were statistically significant(P<0.05).Comparison of results in group: the scores at 3 time points in control group were statistically significant(P<0.05);The scores at three time points in experimental group were statistically significant(P<0.05).7.Effect of intervention on radiation dermatitis:Before intervention,there were 0 cases of radiation dermatitis in the two groups.After 3 weeks of intervention,there were 5 cases of level 0,17 cases of levelⅠ,7 cases of levelⅡ,2 cases of levelⅢ in the control group;there were 7 cases of level 0,17 cases of levelⅠ,4 cases of levelⅡ,3 cases of level Ⅲ in the experimental group;After6 weeks of intervention,there were 19 cases of levelⅠ,4 cases of levelⅡ,8 cases of level Ⅲ in the control group,there were 7 cases of level 0,19 cases of levelⅠ,3 cases of levelⅡ,2 cases of level Ⅲ in the experimental group.The two groups before and after the intervention had no level Ⅳ.Comparison between groups: After 3 weeks of intervention,there was no significant difference between the two groups(P<0.05).After 6 weeks of intervention,the degree of radiation dermatitis between the groups was statistically significant(P<0.05).Conclusion1.The effect of aerobic exercise combined with CBT on the improvement of cancer-related fatigue in patients with breast cancer receiving radiotherapy was better than that of aerobic exercise alone,especially in terms of overall fatigue,severity,and cognitive/emotional dimensions.2.The effect of aerobic exercise combined with CBT on improving the quality of life of patients with breast cancer receiving radiotherapy was better than that of aerobic exercise alone,especially in the dimensions of overall quality of life,social and family well-being,and functional well-being.3.The effect of aerobic exercise combined with CBT on reducing anxiety and depression of patients with breast cancer receiving radiotherapy was better than that of aerobic exercise alone.4.The effect of aerobic exercise combined with CBT on reducing the degree of radiation dermatitis is better than that of aerobic exercise alone. |
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