Epidemiology And Follow-up Study Of Cognitive Impairment In A Community In Xilin Gol League,Inner Mongolia

Objective Through the diagnosis,epidemiological investigation and follow-up study of the elderly over 55 years of age in a community in the Ulagai Management District of Xilin Gol League,Inner Mongolia Autonomous Region,we can understand the general classification of cognitive dysfunction in the community and make statistics on related factors.Scientific analysis to provide certain support for community screening,prevention and intervention of high-risk groups;through three-year follow-up study,the diagnosis of Alzheimer’s disease is further clarified,and for the development of Alzheimer’s disease prevention and control strategies and elderly health in the Inner Mongolia Autonomous Region community Health services provide a reference basis.Methods a.Survey method Select the permanent population over 55 years old in a community in the Ulagai Management District of Xilin Gol League,Inner Mongolia Autonomous Region,as the survey objects,and conduct on-site questionnaires.(1)The first stage: first ask for general information,including personal information,living habits,past medical history,life,social behavior,etc.and complete the assessment of the ability of daily living(ADL),and then use the simple mental status check(MMSE)scale Scoring,the subjects who are less than the scoring standard will be investigated in the second stage.(2)The second stage: Clinical diagnosis:①Diagnostic criteria: This survey uses the fourth edition of the American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders Revised 4th Edition(DSM-IV)to diagnose dementia;in 2011,the National Institute of Aging(NIA)and the Alzheimer’s Association(AA)established the NIA-AA(2011)diagnosis to diagnose AD;②Cognitive scale assessment: If the MMSE scale initially screens for suspected cognitive dysfunction,further improve Montreal’s cognition Assessment Scale(Mo CA)and Hachinski Ischemic Scale(HIS)evaluation.For individuals with doubts about the diagnosis,perform neurological examination,CT or MRI imaging examination,blood routine,biochemical and other laboratory tests;(3)The third stage: follow up the above population regularly every year,repeat the above steps,conduct questionnaire survey and cognition Functional evaluation.b.Statistical methods: SPSS22.0 performs statistical analysis on data,including indicators such as the adoption rate of counting data and composition ratio;measurement data uses indicators such as mean and standard deviation.Single factor chisquare test was used for influencing factors,logistic regression analysis was used for multifactor analysis;t test was used for three-year follow-up data.Results(1)Basic information: This study effectively investigated 1543 people,including663 males with an average age of(68.37±7.53)years old,and 880 females with an average age of(68.39±7.62)years old.The age distribution is mainly concentrated in 65-75 years old,followed by 55-65 years old,and the population over 85 years old is the least.The Han nationality is the dominant ethnic group,accounting for 79%,followed by the Mongolian nationality,accounting for 18.6%.Marital status is mainly married,accounting for 82.4%.In this community,illiteracy and elementary school are the main education level of the elderly over 55 years old,accounting for 58.8%;the education level above junior high school accounts for 41.2%.72.3% of the elderly in this community exercise once every 2-3 days,and each exercise lasts for 1-2 hours.(2)The prevalence of Alzheimer’s disease and its influencing factors: A total of 87 patients with dementia were diagnosed through a three-year follow-up study,with a total prevalence rate of 5.63%,including 10 people with vascular dementia,1person with mixed dementia,and Alzheimer’s 76 people with silent disease,the prevalence rates were 0.64%,0.065%,and 4.93%,respectively.Alzheimer’s disease is the main cause of cognitive impairment in this community,accounting for 87.3%.Single factors associated with AD include gender(c =3.393,P=0.022),age(X2 = 10.843,P=0.013),education level(X2=19.391,P=0.00),marital status(X2 =3.944,P=0.047),family income(X2 =10.366,P=0.016),BMI(X2 =6.856,P=0.009),smoking(X2 =5.773,P=0.016),exercise frequency(X2 =27.456,P=0.000),Are statistically significant.Multivariate logistic regression showed that advanced age((OR=1.034,95%CI=1.004～1.065)),no exercise(OR=2.020,95%CI=1.310～3.114),low education level(OR=1.802,95%)CI=1.330～2.441)is a risk factor for Alzheimer’s disease.Married(OR=0.328,95%CI=0.158～0.681)and high annual income(OR=0.803,95%CI=0.645～0.998)are the risk factors for Alzheimer’s disease.Protective factors of Zheimer’s disease.(3)Three-year follow-up study: The t-test on the three-year Mo CA scale scores through the follow-up study showed that the total score of the scale decreased year by year.Among them,the visual space ability,delayed memory ability,and language ability decreased the most.