Clinical Observation Of Transcranial Repetitive Acupuncture In The Treatment Of Post-stroke Depression

Objective: To observe the clinical effect of transcranial repeated acupuncture combined with sertraline hydrochloride in the treatment of post-stroke depression,and to provide better treatment methods and ideas for the treatment of post-stroke depression in the future.Method: Sixty-six patients who met the inclusion criteria were selected and divided into the treatment group and the control group according to the random number table method.A total of 4 patients were removed or removed,leaving 62 patients.The final number of patients who completed the trial was 32 patients in the treatment group and 30 patients in the control group.Both groups received the same basic treatment of apoplexy.On the basis of basic treatment,the treatment group was treated with transcranial repeated acupuncture,Shenting and bilateral Benshen points(Zhisanzhen)were taken at acupoints,30 min each time,once a day;The control group was treated with oral sertraline hydrochloride tablets,50 mg each time,once a day.Both groups were treated continuously for 4 weeks.The HAMD-24,NIHSS and ADL scoring scale evaluation results of two groups of patients before,after 2 weeks and after 4 weeks of treatment were respectively compared,and the clinical efficacy of two groups of patients and the correlation analysis between HAMD score,ADL score and NIHSS score of two groups of patients before,after 2 weeks and after 4weeks of treatment were compared.All the above data were statistically analyzed using SPSS25.0 software.Result:1.Before treatment,there were no significant differences in age,course of disease,gender,HAMD-24 score,ADL score and NIHSS score between the two groups(P>0.05),indicating comparability;2.Comparison of scores of various scales:2.1HAMD-24 scoreWithin the treatment group,HAMD-24 scores of the treatment group after 2 weeks and4 weeks of treatment were lower than those before treatment,the difference was statistically significant(P<0.05).The scores of the control group after 2 weeks of treatment were not significantly different from those before treatment(P>0.05).The scores of the control group after 4 weeks of treatment were significantly different from those before treatment(P<0.05).After 2 weeks of treatment,scores in the treatment group were lower than those in the control group,and the difference was statistically significant(P<0.05).After 4 weeks of treatment,scores in the two groups were compared,and the difference was not statistically significant(P>0.05).2.2 NIHSS scoreWithin groups,the NIHSS scores of the treatment group after 2 weeks and 4 weeks of treatment were lower than those before treatment,the difference was statistically significant(P<0.05);the scores of the control group after 2 weeks and 4 weeks of treatment were lower than those before treatment,the difference was statistically significant(P<0.05).After 2weeks of treatment,scores in the treatment group were lower than those in the control group,and the difference was statistically significant(P<0.05).After 4 weeks of treatment,scores in the two groups were compared,and the difference was not statistically significant(P>0.05).2.3 ADL scoresWithin the treatment group,ADL scores of the treatment group after 2 weeks and 4weeks of treatment were lower than those before treatment,the difference was statistically significant(P<0.05);ADL scores of the control group after 2 weeks and 4 weeks of treatment were lower than those before treatment,the difference was statistically significant(P<0.05).After 2 weeks of treatment,scores in the treatment group were lower than those in the control group,and the difference was statistically significant(P<0.05).After 4 weeks of treatment,scores in the two groups were compared,and the difference was not statistically significant(P>0.05).3.Comparison of clinical efficacyAfter 2 weeks of treatment,the total effective rate was 68.8% in the treatment group and 53.3% in the control group.The difference was statistically significant by rank sum test(P<0.05).After 4 weeks of treatment,the total effective rate was 87.5% in the treatment group and 83.3% in the control group.The difference was not statistically significant by rank sum test(P>0.05).4.Correlation analysisBefore treatment,2 weeks after treatment and 4 weeks after treatment,NIHSS score and HAMD score were correlated(P<0.01),and ADL score and HAMD score were correlated(P<0.01).Conclusion:1.Both transcranial repeated acupuncture and oral sertraline hydrochloride tablets can relieve the depression of PSD patients,improve the ability of daily living,and promote the recovery of neurological function,and the effect of transcranial repeated acupuncture is faster.2.The degree of depression after stroke is correlated with the degree of neurological impairment and the ability of daily living.