| Objective to investigate the clinical significance of SIRS,CRP and PCT in early diagnosis of postoperative anastomotic leakage of colorectal cancerMethods A total of 76 patients with colorectal cancer undergoing radical resection in the Department of Gastroenterology,the First Affiliated Hospital of Chongqing Medical University from 2018 to 2019 were retrospectively analyzed.According to the occurrence of anastomotic leakage,the patients were divided into anastomotic leakage group(n = 19)and non anastomotic leakage group(n = 57),The systemic inflammatory response related indexes including leukocyte,CRP,PCT,body temperature,heart rate and respiratory rate were collected on the 1st,3rd and 7th day after operation(the maximum value of the day was taken).Results There was no significant difference in the incidence of CRP,PCT and SIRS between the two groups on the first day after operation(P >0.05).The incidence of CRP,PCT and SIRS in the anastomotic fistula group on the third and seventh day after operation was significantly higher than that in the control group(P < 0.01).Conclusion SIRS,CRP and PCT have certain value for early prediction and diagnosis of anastomotic leakage.If CRP and PCT continue to increase significantly after operation and accompanied with systemic inflammatory response syndrome,the possibility of subsequent anastomotic leakage is greatly increased after excluding incision infection,pulmonary infection and urinary tract infection.Further examination should be carried out as soon as possible,and anti infection measures should be taken to maintain adequate drainage Total parenteral nutrition support and other measures to prevent the occurrence and continuous progress of anastomotic leakage,improve the prognosis of patients,reduce the length of hospital stay and hospitalization costs. |
