| Objective:By observing the difference between warming acupuncture and moxibustion and conventional acupuncture in the treatment of Piman of spleen and stomach deficiency and cold after stroke,to explore the efficacy and safety of the first therapy and find its advantages in the treatment of this disease,and to provide a new treatment scheme for the clinical treatment of Piman of spleen and stomach deficiency and cold after stroke.Method:60 patients of the study with Piman of spleen and stomach deficiency and cold after stroke were randomly assigned into a warming acupuncture and moxibustion group and a conventional acupuncture group,with 30 cases in each group.The two groups were both given Xingnaokaiqiao acupuncture and corresponding symptomatic therapy of ischemic stroke and its underlying diseases,such as anticoagulant lower the blood pressure and glucose and so on.In addition,in view of the Piman of spleen and stomach deficiency and cold after stroke,we set the therapeutic rule of Jianpihewei and Wenzhongxiaopi.And the conventional acupuncture group was only treated with filiform acupuncture.Then,the selected acupoints included: Zhong Wan(CV 12),Tian Shu(ST 25),Guan Yuan(RN 4),Qi Hai(RN 6),Zu Sanli(ST36),Gong Sun(SP 4)and Nei Guan(PC 6),while the other group was given warming acupuncture at Zhong Wan,Guan Yuan and Zu Sanli on the basis of conventional acupuncture treatment.The both groups retained the needle for 30 minutes each time,6 times a week,for a total of 2 weeks.In this study,it’s neccessary to keep a record of the improvement of TCM symptoms score of Piman of spleen and stomach deficiency and cold after stroke,the quality of life index(QOL)of the two groups before treatment and after 1-week and 2-week intervention,the changes of score of self-rating depression scale(SDS)before and after the intervention,and the recurrence rate of Piman symptoms at 1 month after treatment,which could help to evaluate the clinical efficacy.Besides,Paying attention to the occurrence of adverse reactions during the case control study to assess the security.Then,the experimental results were recorded in details and analyzed by SPSS25.0 statistical software.Results:1.There was no statistical difference in age,sex,occurrence of basic diseases,total score of TCM symptoms of Piman of spleen and stomach deficiency and cold after stroke and the individual score of abdominal distention,epigastric preference for warm and pressing,acid regurgitation,anorexia,fatigue,low-temperature of hands and feet,watery stool,and QOL and SDS scores between the two groups before treatment(P>0.05).So it’s comparable between the two groups.2.After 2-week treatment,the total effective rate was 96.67% in the warming acupuncture and moxibustion group versus 76.67% in the conventional acupuncture group,which has obviously statistical difference(P < 0.01).That means the curative effect of warming acupuncture group was significantly better than that of conventional acupuncture group.3.Self-made spleen and stomach deficiency and cold type of Piman in TCM symptoms score:(1)Intra-group comparison:(1)After 1-week and 2-week therapeutic intervention,the individual score of abdominal distention,epigastric preference for warm and pressing,anorexia and watery stool and the total scores of Piman in the conventional acupuncture group were all obviously lower than those before treatment(P<0.01).The score of fatigue in this group decreased,too(P<0.05).However the score of low-temperature of hands and feet did not change significantly(P>0.05).What’s more,the individual score of acid regurgitation in this group didn’t have significantly change after 1-week treatment(P>0.05),but after 2-week treatment,it was obviously lower than that before treatment(P<0.01).(2)After 1and 2-week therapeutic intervention,the individual score of abdominal distention,epigastric preference for warm and pressing,anorexia and watery stool and the total scores of Piman in the warming acupuncture and moxibustion group were all obviously lower than those before treatment(P<0.01).After 1-week treatment,the scores of acid regurgitation and fatigue in this group both decreased(P<0.05),but the score of low-temperature of hands and feet did not change significantly(P>0.05).After 2-week treatment,the scores of acid regurgitation,fatigue and low-temperature of hands and feet in the warming acupuncture and moxibustion group were all obviously lower than those before treatment(P<0.01).(2)Comparison between the two groups:After 1-week treatment,the total scores of Piman and the score of epigastric preference for warm and pressing in the warming acupuncture and moxibustion group were significantly lower than those in the other group(P<0.01),and the scores of abdominal distention and watery stool in this group were also lower than those in the other group(P<0.05),but there was no statistically differences in the scores of acid regurgitation,anorexia,fatigue and low-temperature of hands and feet between the two groups(P>0.05).While the total scores of Piman and the scores of abdominal distention,epigastric preference for warm and pressing and watery stool in the warming acupuncture and moxibustion group were all significantly lower than those in the other group after 2-week therapeutic intervention(P<0.01),but there still was no statistically differences in the scores of acid regurgitation,anorexia and fatigue between the two groups(P>0.05),while the score of low-temperature of hands and feet in the heat acupuncture group was obviously lower than that in the other group(P<0.01).4.QOL score: After 1-week and 2-week treatment,the scores of the two groups were both lower than those before treatment(P<0.01).And the QOL score of the warming acupuncture and moxibustion group was lower than that of the conventional acupuncture group after1-week treatment,and the score of the warming acupuncture and moxibustion group was significantly lower than that of the conventional acupuncture group after 2-week treatment.5.SDS score:The SDS score of the two groups both decreased obviously after 2 weeks,and the score of the warming acupuncture and moxibustion group was significantly lower than that of the conventional acupuncture group after treatment(P<0.01).6.Recurrence rate: One month after treatment,the recurrence rate in the warming acupuncture and moxibustion group was 6.67%,which was lower than 26.67% in the conventional acupuncture group(P<0.05).7.Safety evaluation and adverse reaction observation: As for the safety evaluation,there were 28 cases of grade 1 and 2 cases in the warming acupuncture and moxibustion group,and the incidence of adverse reactions was 6.67%;while in the conventional acupuncture group,there respectively had 29 cases and 1 case,so the rate was 3.34%.There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:1.Both warming acupuncture and moxibustion and conventional acupuncture can effectively improve the clinical symptoms of patients with Piman of spleen and stomach deficiency and cold after stroke,but the curative effect of warming acupuncture and moxibustion group is better.2.Compared with the conventional acupuncture group,the warming acupuncture and moxibustion therapy had more obvious improvement on abdominal distention,epigastric preference for warm and pressing,low-temperature of hands and feet and watery stool.On the other hand,the two therapies have similar effect in the treatment of acid regulation,anorexia,fatigue,but the warming acupuncture and moxibustion therapy toke effect more quickly on acid regurgitation.3.Both warming acupuncture and moxibustion therapy can significantly improve the quality of life of patients with Piman of spleen and stomach deficiency and cold after stroke,and relieve their depression.But compared with the conventional acupuncture group,the recurrence rate of warming acupuncture and moxibustion group is lower,and its long-term effect is better.4.Warming acupuncture and moxibustion therapy in the treatment of Piman of spleen and stomach deficiency and cold after stroke is safe and has a low incidence of adverse reactions.It is also reliable and effective.Therefore,patients are easy to accept the therapy and have high compliance.Then it can provide new ideas and programs for clinical treatment of this disease. |
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