A Real-world Study Predict 90-day Risk In Patients With Primary Lung Cancer Chinese Medicine Treatment

Purpose: The purpose of this study is to test the risk factors of prognostic risk of primary lung cancer by establishing a real-world model of 90-day mortality risk in patients with primary lung cancer treated by Chinese medicine,to predict the risk of death in patients with primary lung cancer,to provide reference for the prognostic and survival of primary lung cancer patients,and to scientifically evaluate treatment objectives,formulate reasonable treatment plans,reduce the burden on patients,With a view to facilitating my future clinical work.Methods: Collected 240 cases of primary lung cancer patients admitted to hospital from July 01,2019 to September 31,2020 in the Oncology Department of Jiangxi Provincial Hospital,recorded the general data of patients,and included the relevant indicators in the study.Pay close attention to the patient’s condition during hospitalization,from the day of hospitalization to the 90 th day,or the patient died within 90 days,through follow-up and modern means of communication to continue to obtain relevant information,organize data and information input Excel table,import statistical software in turn for all variables for single-factor analysis,screening out statistically significant variables for multi-factor analysis,explore chinese medicine treatment involved in primary lung cancer patients 90 days of death independent predictors,establish a regression equation.The predicted value of 90-day death of PLC patients treated with Chinese medicine and the best truncation value were determined by ROC curve,and the predicted value of the model was judged.Results: Based on the multi-factor analysis of the binary logistic line,it is found that PLL(OR=1.015,95% Cl 1.004-1.027,P=0.008),BMI(OR=0.557,95%Cl 0.374-0.828,P=0.004),TCM participation in treatment(OR=0.055,95% Cl 0.003-1.197,P=0.004),TCM waiting type(OR=19.02,95% Cl 3.427-105.607,P<0.05),Jaundice use or not(OR=193.475,95% Cl 14.014-2671.089,P<0.05)jaundice dose(OR=1.085,95%Cl1.019-10156,P=0.011)and the patient’s lifestyle(OR=0.035,95% Cl0.006-0.195,P<0.05)is statistically significant,with PLR,BMI,and TCM involved in the treatment The waiting type of Chinese medicine certificate,whether to use jaundice,jaundice dose and lifestyle are independent predictive factors of 90-day mortality risk in patients with primary lung cancer treated by Chinese medicine.It was analyzed with ROC curve pair,PLR’s AAUC was 0.912(P<0.05),the best truncation value ≥163.5,with 85.9% sensitivity and 86.5%specificity.BMI’s AAUC is 0.746(P<0.05),the best truncation value≤18.9115,with 66.3% sensitivity and 79.7% specificity,the AUC of Chinese medicine participating in treatment is 0.722(P<0.05),the best truncation value ≤0.5,with 51.5 1% sensitivity and 93.2%specificity,AUC of TCM waiting type 0.645(P<0.05),best truncation value ≤1.5,with 35.9% sensitivity and 92.6% specificity,jaundice use or not AUC 0.709(P<0.05),best truncation value ≤0.5,with 75%sensitivity and 66.9% specificity,jaundice dose AUC of 0.619(P=0.002),best truncation value ≤5,With 70.7% sensitivity and52.7% specificity,lifestyle AUC s 0.709(P<0.05),the best truncation value ≤0.5,with 39.1% sensitivity and 99.3% specificity.Regression Equation Y=10.052+0.015*NLR-0.339*BMI-2.894* Chinese medicine is involved in the treatment +2.946* Chinese medicine certificate waiting type +5.265* Jaundice is used +0.082* The dose of jaundice-3.346* Lifestyle,the Chinese medicine treatment PLC patients 90 days of death risk has a better predictive value.Joint pre-test because sub-Y AUC is 0.738(P<0.05)best truncation value ≥13.091,with 55.4% sensitivity and 88.5% specificity,has a good reference value.Conclusion: PLR,BMI,Chinese medicine participation in treatment,Chinese medicine certificate waiting type,whether to use jaundice,jaundice dose,lifestyle as an independent factor of 90 days of death risk for PLC patients treated by Chinese medicine,regression equation Y=10.052+0.015*NLR-0.339*BMI-2.894* Chinese medicine is involved in the treatment +2.946* Chinese medicine certificate waiting type +5.265* Jaundice is used +0.082* The dose of jaundice-3.346* Lifestyle,The risk of death of PLC patients treated with Chinese medicine was better predicted.