Study On The Distribution Characteristics Of TCM Syndrome Elements In Diarrheal Irritable Bowel Syndrome With Overlapping Functional Dyspepsia

Objective: To study the distribution characteristics of TCM syndrome factors of diarrhea-type irritable bowel syndrome with overlapping functional dyspepsia through the theory of syndromes,improve the distribution of syndrome types of diarrhea-type irritable bowel syndrome with overlapping functional dyspepsia,and provide help for clinical differentiation of TCM syndromes.Methods: Collect 120 cases of IBS-D overlapping FD patients in outpatient and inpatient departments of Fuzhou Hospital of Traditional Chinese Medicine,collect the general information of the patients and the information of the four clinics,extract the corresponding disease location and disease characteristics,collect the data to establish a database,and use statistical analysis,To explore the distribution characteristics of TCM syndrome elements and syndrome types in patients with IBS-D overlapping FD.Results:1.Among the 120 patients,47 were males,accounting for 39.17%,73 were females,accounting for 60.83%,and the ratio of male to female was 1:1.55.The oldest is 67 years old and the youngest is 19 years old.The age of onset is mainly between 18 and 59 years old,with an average age of 41.10±8.97 years.The difference in the distribution of gender and age was statistically significant(P<0.05).2.The distribution characteristics of IBS-D overlapping FD syndrome elements:(1)The disease location syndrome elements include 8 spleen,stomach,liver,large intestine,small intestine,kidney,thoracic diaphragm,and gallbladder,of which the spleen appears most frequently(102 cases,85.00%)The rest were stomach(95 cases,79.17%),liver(34cases,28.33%),large intestine(28 cases,23.33%),small intestine(20 cases,16.67%),and kidney(15 cases,12.50%).After statistical testing,there are significant differences in the distribution of syndrome elements in each disease location.The spleen and stomach are compared with other disease locations,and the differences are statistically significant(P<0.05),and there is no significant difference in the distribution between the spleen and stomach(P>0.05),there was no significant difference in the distribution of liver,large intestine,small intestine,and kidney(P>0.05).(2)There are 11 disease-related syndromes including Qi stagnation,dampness,Yang deficiency,Qi deficiency,heat,Yin deficiency,blood deficiency,cold,food accumulation,blood heat,and qi depression.The most frequent occurrence is Qi stagnation(112 cases,93.33%),the rest were wet(91 cases,75.83%),Yang deficiency(57 cases,47.50%),Qi deficiency(49 cases,40.83%),heat(43cases,35.83%),Yin deficiency(36 cases,30.00%).After statistical testing,there are significant differences in the distribution of syndrome elements of various diseases(P<0.05).Among them,stagnation of qi,dampness and other diseases have statistically significant differences(P<0.05).Yang deficiency,dampness,and dampness are significantly different from those of other disease syndromes(P<0.05).There was no significant difference among Qi deficiency,heat and Yin deficiency(P>0.05).3.IBS-D overlapping FD can be divided into 5 types of syndromes,namely,spleen deficiency and dampness syndrome,liver depression and spleen deficiency syndrome,spleen and stomach damp-heat syndrome,spleen and kidney yang deficiency,and spleen and stomach yang deficiency syndrome.Among them,the syndrome of spleen deficiency and dampness was the most frequent,with 37 cases,accounting for 30.83%.The rest were followed by liver depression and spleen deficiency syndrome(34 cases,28.33%),spleen and stomach damp-heat syndrome(32 cases,26.67%),spleen and kidney Yang deficiency(9 Cases,7.5%),spleen and stomach yang deficiency syndrome(8 cases,6.67%).According to statistical tests,the differences of spleen deficiency and dampness syndrome,liver depression and spleen deficiency,and spleen and stomach damp-heat syndrome were statistically significant compared with spleen-kidney-yang deficiency and spleen-stomach-yang deficiency(P<0.05).Conclusions:1.Among the patients with IBS-D overlapping FD,the incidence of women is higher than that of men,and it is more common in young and middle-aged people aged 18-59.2.The pathological factors of IBS-D overlapping FD are spleen,stomach,liver,large intestine,small intestine,kidney,thoracic diaphragm,and gallbladder.Among them,the spleen and stomach appear most frequently,indicating that the spleen and stomach are the main lesions of IBS-D overlapping FD,and are closely related to the liver,large intestine,small intestine,and kidney;disease syndromes include stagnation of qi,dampness,yang deficiency,qi deficiency,and heat,Yin deficiency,blood deficiency,cold,food accumulation,qi depression,blood heat,of which qi stagnation and dampness occur most frequently,indicating that qi stagnation and dampness are the main disease factors of IBS-D overlapping FD.3.The most common type of IBS-D overlap FD is spleen deficiency and dampness,followed by liver depression and spleen deficiency,spleen and stomach damp-heat syndrome,spleen and kidney yang deficiency,and spleen and stomach yang deficiency are rare.