The Preliminary Study On The Distribution Characteristics Of Different Types Of Chronic Gastritis With Bile Reflux Syndrome

ObjectiveChronic gastritis with bile reflux is a common clinical disease.It has a long course and is prone to recurring attacks.In recent years,the proportion of the disease has been on the rise.Modern studies have found that the severity of bile reflux is positively correlated with the degree of gastric mucosal inflammation and repeated bile stimulation can aggravate gastric mucosal damage,causing erosion,ulcers,atrophy,intestinal metaplasia and even gastric cancer.Therefore,this study established the syndrome differentiation method to observe and analyze the phenomenon of different types of chronic gastritis with bile reflux,summarized and analyzed the distribution characteristics of the two syndromes and their differences.In order to achieve the purpose of providing reference basis for clinical syndrome differentiation and treatment of traditional Chinese medicine and reduce the risk of cancer.MethodsThis study collected patients from January 2020 to January 2021 in The Second Affiliated Hospital of Fujian Traditional Chinese Medical University from January 2020 to January 2021.The 140 cases of chronic gastritis with bile reflux who were diagnosed by electronic gastroscopy and pathological examinations had clinical symptoms and met the exclusion and inclusion criteria.The 140 cases were divided into chronic non-atrophic gastritis(CNAG)with bile reflux group and chronic atrophic gastritis(CAG)with bile reflux group.Through face-to-face questionnaires,survey and collected basic data on population distribution characteristics such as gender,age,eating habits,body mass index(BMI),degree of reflux and histopathological changes in gastric mucosa and then collected information from four clinics to fill in chronic gastritis.Used the syndrome differentiation software(Chinese medicine health status identification and consultation system)to calculate the syndrome element distribution of CNAG with bile reflux group and CAG with bile reflux group and analyzed the differences and other characteristics with the information table of syndrome elements with bile reflux.Results1.There is no difference between the two groups in the distribution of gender,age,degree of bile reflux and BMI.2.Correlation between the degree of reflux of chronic gastritis with bile reflux and the histopathological changes of gastric mucosa:the degree of histopathological changes of gastric mucosa such as chronic inflammation,atrophy and intestinal metaplasia is positively correlated with the degree of bile reflux.The degree of activity changes is positively correlated with The degree of bile reflux has no obvious correlation.3.The syndrome elements on disease location of CNAG with bile reflux are mainly comsists of stomach,liver and gallbladder.It’s also involves spleen,mind,half surface and half lining,large intestine,small intestine,kidney,heart,thoracic diaphragm and uterus.The main syndrome elements on disease nature of CNAG with bile reflux are comsists of qi stagnation,heat,dampness,yin deficiency and also involves phlegm,qi deficiency,food accumulation,blood stasis,yang deficiency,yang hyperactivity,blood deficiency,cold,blood heat and drinking.4.The syndrome elements on disease location of CAG with bile reflux are mainly comsists of stomach,spleen,liver and gallbladder,as well as involve half-surface and half-inner,kidney,large intestine,small intestine,mind,uterus and heart.The main syndrome elements on disease nature of CAG with bile reflux are comsists of qi stagnation,dampness,qi deficiency,phlegm and yin deficiency,as well as involve heat,yang deficiency,blood stasis,blood deficiency,food accumulation,yang hyperactivity,drinking and cold.5.There are statistically significant differences between the CNAG with bile reflux group and the CAG with bile reflux group in the level distribution of the disease-location-syndromes of spleen and gallbladder(P<0.05).There are statistically significant differences between the CNAG with bile reflux group and the CAG with bile reflux group in the level distribution of the disease-nature-syndromes of qi deficiency,yang deficiency,dampness,phlegm and blood stasis(P<0.05).Conclusion:1.Chronic gastritis with bile reflux is related to the stomach,liver,spleen and gallbladder.The main disease-location of CNAG with bile reflux are in the stomach,liver and gallbladder.The main disease-location of CAG with bile reflux are in the stomach,spleen,liver and gallbladder and spleen and gallbladder are related to the progression of the disease.2.Chronic gastritis with bile reflux.The main disease-nature of CNAG with bile reflux are qi stagnation,heat,dampness,yin deficiency.The main pathogenic factors of CAG with bile reflux is the main disease-nature elements are significant in qi stagnation,dampness,qi deficiency,phlegm and qi deficiency and qi deficiency,yang deficiency,dampness,phlegm and blood stasis are related to disease progression.3.It is suggested that the treatment of chronic gastritis with bile reflux should take into account the specimens and the principles of soothing the liver and regulating qi,invigorating the spleen and dampness,replenishing qi and stomach,clearing away heat,nourishing yin and promoting bile.The CNAG with bile reflux pays attention to soothing the liver and regulating qi,clearing away heat and dampness and nourishing yin in the stomach.The CAG with bile reflux pays attention to strengthening the spleen and regulating qi,supplemented by the stomach to dissolve dampness,soothing the liver and promoting bile.And it is also necessary to pay attention to the application of the method of expectorating and removing blood stasis.