Clinical Observation On The Treatment Of Liver And Kidney Deficiency Type Of Knee Osteoarthritis With Yangxue Qiangjin Ointment Combine With Tai Chi

Objective: To observe the clinical efficacy and safety of Yangxue Qiangjin ointment,Tai Chi and Yangxue Qiangjin ointment combined with Tai Chi in the treatment of Liver and Kidney Deficiency Type knee osteoarthritis and explore the optimal treatment plan and to supply reference for the treatment of knee osteoarthritis patients.Methods: 90 patients with knee osteoarthritis who met the diagnostic,inclusion and exclusion criteria were selected(those who live in Zhengzhou and surrounding areas for a long time are preferred).SPSS software was used to randomly divide the included cases into the Yangxue Qiangjin ointment group(ointment group),Tai Chi group,and Yangxue Qiangjin ointment combined with Tai Chi group(combination group),30 cases in each group.All three groups received basic treatment with Glucosamine Sulfate Capsules and health education.On the basis of treatment,the ointment group was given treatment of Yangxue Qiangjin ointment,the Tai Chi group was given Tai Chi exercise,and combination group was given Yangxue Qiangjin ointment combined with Tai Chi exercise.After 8 weeks of treatment,statistical analysis before and after treatment was performed on VAS score,WOMAC score,knee flexion and extension muscle group PT values,TCM syndromes scores and untoward effect.Results: A total of 90 subjects were included in this study,and 86 subjects were actually analyzed.(1)Compared with before treatment,data such as gender,age,course of disease,K-L imaging grade and VAS scores,WOMAC scores,knee flexion and extension muscle group PT values,TCM syndrome among the three groups showed no significant difference(P>0.05)and was comparable.(2)VAS score: VAS score of all the three groups tailed off compared with that before therapy,and the difference had statistical meaning(P<0.05).Comparison between the three groups manifested that VAS score of the combination group was clearly under that of the ointment group and the Tai Chi group,and the difference showed statistical meaning(P<0.05).The difference that VAS score of the ointment group was under that of the Tai Chi group was statistically meaning(P<0.05).(3)WOMAC score: In terms of knee pain,stiffness,and joint function,compared with that before therapy,the difference that WOMAC score of all the three groups went down had statistical meaning(P<0.05).Comparison between the three groups manifested that WOMAC score of the combination group was clearly under that of the ointment group and the Tai Chi group,and the difference had statistical meaning(P<0.05).The difference that WOMAC score of the ointment group was under that of the Tai Chi group was statistically meaning(P<0.05).(4)Knee flexion and extension muscle group PT values: Comparison within the group,after treatment,the difference that the knee flexion and extension muscle group PT values of the three groups of patients enhanced compared with those before treatment showed statistical meaning(P<0.05).In comparison between groups,knee flexion and extension muscle group PT values in the combination group was obviously more than that in the Tai Chi group and the ointment group,and the difference revealed statistical meaning(P<0.05).The difference that the knee flexion and extension muscle group PT values in the Tai Chi group was greater than that in the ointment group revealed statistical significance(P<0.05).(5)TCM syndromes scores:The effects of the three groups after therapy manifested that TCM syndromes scores was less than that before therapy,and the difference manifested statistical meaning(P<0.05).In comparison between groups,the difference that the TCM syndromes scores of the combination group was less than that of the ointment group and the Tai Chi group indicated statistical meaning(P<0.05).The difference that the TCM syndrome score of the ointment group was lower than that of the Tai Chi group revealed statistical meaning(P<0.05).(6)Clinical efficacy:The total clinical effective rate of the ointment group was 86.21%,the Tai Chi group was 75.00% and the combination group was 93.10%.There was a statistically meaning between the three groups(P<0.05)in clinical efficacy after treatment.The difference that the combination group kept eminently better efficacy than the Tai Chi group and the ointment group indicated statistical meaning(P<0.05).The difference that the ointment group kept better efficacy than the Tai Chi group indicated statistical meaning(P<0.05).(7)Safety results: During the treatment period,none of the three groups of patients experienced gastrointestinal reactions,skin itching,rashes,and other sudden illnesses.Safety index is in the normal range.Conclusion: On the basis of Glucosamine Sulfate Capsules and health education,the three therapies of Yangxue Qiangjin ointment,Tai Chi and Yangxue Qiangjin ointment combined with Tai Chi can reduce knee joint VAS score,WOMAC score and TCM syndromes scores in patients with liver and kidney deficiency knee osteoarthritis,and increase knee flexion and extension muscle group PT values,the safety is higher,of which the ointment group VAS score,WOMAC score and TCM syndromes scores improved better than Tai Chi group,the improvement of knee flexion and extension muscle group PT values of Tai Chi group better than the ointment group,and the improvement of the above indexes in combination group was eminently superior to that in the ointment group and the Tai Chi group,which is worthy of clinical reference and further research.