Study On The Correlation Between TCM Constitution And Syndrome Differentiation Of Gallbladder Polypoid Transformation

Objective: To study the distribution of the constitution type and syndrome type of gallbladder polyps,and to explore the possible correlation between them,and to provide scientific basis for prevention and treatment of the disease from the perspective of TCM Constitution.Methods: according to the inclusion standard and exclusion standard,136 patients with gallbladder polyps were included.The general data,four diagnosis data of TCM,physical type data and imaging examination(abdominal B-ultrasound)were collected.The data base was created,and the distribution of TCM Constitution and syndrome differentiation was studied by using chi square test and Fisher test.The correlation between them was analyzed.The influence of age,sex,smoking,drinking,quantity,size and complication of gallbladder polyps on TCM Constitution and syndrome differentiation were analyzed.Result:1.the most frequent clinical symptoms of gallbladder polyps are full chest and flank,followed by threatening pain,belching,abdominal distention,stomachache,nausea and retch,and weak mouth.2.the single occurrence of gallbladder polyps was 58.1%,and the multiple was 41.9%,and the single one was more common.the polyps with diameter less than 5mm accounted for 56.6%,5mm-10 mm polyps accounted for 43.4%,and the more common ones were smaller than 5mm.3.cholecystitis accounted for 26.7%,gallbladder stones 18.6%,fatty liver 54.7%.The results showed that the most common cases of gallbladder polyps and fatty liver were cholecystitis and gallstone.4.the distribution of TCM syndrome differentiation and classification in patients with gallbladder polyps: the most common syndrome was liver depression and spleen deficiency(35.29%),phlegm damp and damp obstruction(25.00%),stagnation of liver and gallbladder Qi(19.12%),damp heat syndrome of liver and gallbladder(13.97%),blood stasis and collaterals obstruction(6.62%).There were some correlation between the syndrome differentiation and gender(P < 0.05).In this study,the male was more likely to have liver depression and spleen deficiency,and women more had liver and gallbladder qi stagnation.The distribution of TCM syndrome type was correlated with the gallbladder polyp with fatty liver(P < 0.05),the most common syndrome was liver depression and spleen deficiency,followed by phlegm dampness.There was no significant correlation between age,smoking,drinking,number of polyps,size of polyps,cholecystitis,gallstone and distribution of syndrome differentiation in TCM(P > 0.05).5.the distribution of constitution types in gallbladder polyps were as follows: Qi Depression(26.47%),Qi deficiency(19.12%)were the most common,followed by Yang deficiency(16.91%),phlegm wet matter(12.50%),Pinghe(8.82%),humid and hot matter(6.62%),blood stasis(5.89%),yin deficiency(2.20%),and special quality(1.47%).The distribution of constitution in traditional Chinese medicine was significantly correlated with age(P < 0.05),and qi depression was found in 30-49 years old group,and qi depression and yang deficiency were more common in 50-59 years old group.The distribution of constitution type in TCM was correlated with the gallbladder polyp with fatty liver(P < 0.05),which was mostly found in phlegm wet and qi depression.There was no significant correlation between the distribution of sex,smoking,drinking,number of polyps,size of polyps,cholecystitis,gallstone and constitution type of TCM(P > 0.05).6.there was a significant correlation between the distribution of TCM Constitution and syndrome differentiation(P = 0.000).Qi Qi Qi Qi stagnation syndrome,Qi deficiency and phlegm dampness mostly appear in liver depression and spleen deficiency syndrome,Yang deficiency mostly appear in phlegm damp syndrome,liver depression spleen deficiency syndrome mostly appears in Qi deficiency,qi depression,phlegm dampness syndrome mostly appears in Yang deficiency.Conclusion1.the syndrome differentiation and classification of TCM is the most common syndrome of liver depression and spleen deficiency,followed by syndrome of phlegm damp,stagnation of liver and gallbladder Qi,damp heat of liver and gallbladder,and syndrome of blood stasis and collaterals obstruction.In this study,the male was more likely to have liver depression and spleen deficiency,and women more had liver,gallbladder and qi stagnation.The most common syndrome of liver depression and spleen deficiency is gallbladder polyp combined with fatty liver,and the second is phlegm dampness.2.qi depression and Qi deficiency are the most common physical types in patients with gallbladder polyps,followed by Yang deficiency,phlegm wet quality,Pinghe quality,damp and heat quality,blood stasis quality,yin deficiency quality and special quality.Qi depression was found in the age group of 30-49 years,and qi depression and yang deficiency were found in 50-59 years old.Gallbladder polyps combined with fatty liver are often seen in phlegm wet and qi depression.3.the constitution of traditional Chinese medicine has significant correlation with the distribution of syndrome differentiation.Qi Yu quality is mostly found in the syndrome of stagnation of liver and gallbladder Qi,Qi deficiency and phlegm dampness are mostly in the syndrome of liver depression and spleen deficiency,Yang deficiency mostly appears in phlegm damp,liver depression and spleen deficiency syndrome mostly appear in Qi deficiency and qi depression,and phlegm dampness is mostly in Yang deficiency.