Analysis On Professor Huang Guihua’s Herbal Administration Experiences For Diarrheal Irritable Bowel Syndrome

Objective: By reviewing the clinical medical records of Professor Huang Guihua’s treatment of diarrheal irritable bowel syndrome and statistically analyzing the prescriptions of patients with data mining technique,we can obtain the medication rule of Professor Huang Guihua in treating diarrheal irritable bowel syndrome and summarize Professor Huang Guihua’s clinical experience in the treatment of diarrheal irritable bowel syndrome.Methods: Collating the specific case data of Professor Huang Guihua for the treatment of diarrheal irritable bowel syndrome in outpatient clinic from January 2018 to June 2020,117 eligible patients were identified and collecting the data of clinical cases of 193 visits in all.Establishing a database through Excel tables and uploading medical records with the "Traditional Chinese Medicine Inheritance Computing Platform(V3.0)" to compare the data from the perspectives of medication frequency,medication classification,dosage,four qi,five flavors,meridian and drug compatibility as to frequency analysis and cluster analysis.And preliminarily summarized Professor Huang Guihua’s experience in the treatment of IBS-D.Results: Among the selected 193 Drug prescriptions for diarrheal irritable bowel syndrome,114 Chinese medicines were used in total,the using frequency of data is 1980 times.There are 33 Chinese traditional medicines used more than 10 times.The order is: Atractylodes macrocephala(138 times),roasted licorice(128 times),Amomum(128 times),cardamom(117 times),Poria(112),Epimedium(97 times),malt(85 times),fennel(73 times),Pinellia ginger(71 times),Paojiang(62 times),which are commonly used drugs for the treatment of diarrheal irritable bowel syndrome.In 193 Drug prescriptions,medication is based on tonic,dampness,warming,and digestant drugs.Among them,the most used are tonic drugs,in total 29 traditional Chinese medicines,with a frequency of 604 times,accounting for 30.05%.These four types of drugs are the core drug categories for Professor Huang Guihua’s treatment of diarrheatype irritable bowel syndrome.Statistics on those Drug prescriptions mainly are warm(62.8%),calm(18.6%),and heat(10.6%).Drug properties are focused on warm,calm and heat.Among the five flavors,spicy Chinese medicine is used most.Sweetness and bitterness are the second and third places in order.Tropism of Drug are mainly spleen meridian,stomach meridian,kidney meridian,lung meridian and liver meridian.After clustering analysis(k-means algorithm combined with regression model),there are 5 commonly used drug combinations available to choose from:(1)Atractylodes macrocephala,roasted licorice,epimedium,cassia twig,ginger,Amomum villosum;(2)tangerine peel,ginger pinellia,cardamom,cantonese Agastache,Atractylodes,Amomum;(3)Paojiang,psoralen,roasted licorice,Amomum,Poria,Epimedium;(4)Atractylodes,roasted licorice,dried ginger,cardamom,psoralen,ginseng;(5)Poria,Atractylodes,Codonopsis,ginger pinellia,amomum,cardamom.Conclusion: 1.In terms of medication,in view of the pathogenesis,Professor Huang Guihua’s prescriptions for the treatment of IBS-D are streamlined.The choice of clinical medicine is mainly mild.The overall drug properties are emphasis on yang,tonification and purgation in combination but paying more attention to tonification;On the basis of above,adding dampness-resolving medicinal,interior-warming drug,damp-clearing drug to increase the curative effect;The choice of drug properties is mainlygentle.Tropism of taste: pungent,bitter,sweetness.In the spleen,stomach,kidney.2.Professor Huang Guihua believes that the key to the pathogenesis of IBS-D lies in the insufficiency of both the spleen and the kidney asdthenic splenonephro-yang and the deficiency of cold and damp and hot.the deficiency of cold and damp and hot is the branch,and the insufficiency of both the spleen and the kidney asdthenic splenonephro-yang is rool.The treatment mainly focuses on warming the kidney and strengthening the spleen,especially invigorating spleen and supplementing qi.Supplemented by the method of removing dampness to restore normal functioning of the stomach,warming the interior todissipate cold,clearing damp and promoting diuresis,improving digestion.Clinical prescriptions are mostly based on "guizhi method","huoxiang method","epimedium method","lizhong method","four monarch method" and with the addition and subtraction of the IBS-D in clinical practice to gain "Righteousness is inside,and evil cannot be done."...