Clinical Observation Of Wendan Decoction Combined With Sertraline In The Treatment Of Phlegm Dampness Type Cardiac Syndrome

ObjectiveTo observe the changes of vertigo Disability Assessment Scale(DHI),Hamilton Depression Scale(HAMD),Hamilton Anxiety Scale(HAMA)and clinical symptom assessment scale of traditional Chinese medicine(TCM)before and after the treatment of Wendan Decoction Combined with sertraline in patients with phlegm dampness psychogenic chronic subjective dizziness(CSD),and to comprehensively evaluate the clinical efficacy of Wendan Decoction in the treatment of phlegm dampness psychogenic CSD Objective to explore the safety of traditional Chinese medicine combined with western medicine in the treatment of psychogenic chronic subjective dizziness.Method70 patients with cardiogenic CSD were randomly divided into two groups:the experimental group(n=35)and the control group(n=35).The experimental group was treated with sertraline hydrochloride and Wendan Decoction for 5 weeks,while the control group was treated with sertraline hydrochloride for 5 weeks.By observing the changes of vertigo Disability Rating Scale score,Hamilton Anxiety Scale(HAMA)score,Hamilton Depression Scale(HAMD)score and TCM symptom score before and after 5 weeks of treatment,the efficacy and advantages of traditional Chinese medicine combined with western medicine in the treatment of cardiogenic CSD were evaluated.Result(1)Comparison of baseline data:Before treatment,there was no statistically significant difference in age,gender,and course of disease between the two groups of patients(P>0.05),and they were comparable;(2)Observational project comparison:The difference between DHI score,HAMA score,HAMD score and Chinese medicine certificate waiting points was not statistically significant(P>0.05)in the experimental group and the control group,and the D patients in the 2 groups after treatment were not statistically significant(P>0.05>HI score,HAMA score,HAMD score,Chinese medicine card waiting points were lower than before treatment,the difference was statistically significant(P<0.01);The differences were statistically significant(P<0.05),and the differences between HAMA,HAMD and control groups in the post-treatment experimental group were not statistically significant(P>0.05).(3)Comparison of efficacy:After treatment,there were significant differences in DHI efficacy between the two groups(P<0.05),the total efficiency of the experimental group was better than that of the control group,there were significant differences(P<0.05),and after treatment,there was a significant difference in the efficacy of the two groups of Chinese medicine certificates(P<0.05),and the total efficiency of the experimental group was better than that of the control group(P<05).(4)There were no adverse reactions after treatment in the experimental group,2 adverse reactions after treatment in the control group,which could be alleviated,and no serious adverse reactions in the overall situation.Conclusion(1)Warm bile Tonga minus joint shequlin can more effectively improve the phlegm wet heart-caused CSD patients dizziness,conscious instability and other symptoms,the effect is better than the control group,and less adverse reactions,high safety,worthy of promotion and application;(2)Warm-bile Tonga minus combined sherquolin can effectively relieve depression and anxiety in patients with cardiac-type CSD,and the effect is not inferior to that of the control group.(3)Warm bile Tonga minus joint shequlin can more effectively improve sputum wet-type CSD patients sputum wet evidence,improve the quality of life of patients,the effect is better than the control group.