Effect Of Interval Time Between Prostate Biopsy And Radical Prostatectomy On The Clinical Efficacy And Psychological Status Of Perioperative Patients

Objective: To explore the effect of interval time(IT)between prostate biopsy and radical prostatectomy on the clinical efficacy and psychological status of patients.Methods: The clinical data of 105 patients undergoing laparoscopic radical prostatectomy were retrospectively analyzed.According to the length of IT(≥4 weeks and <4 weeks),the patients were divided into two groups.Perioperative and general information of patients were collected,including age,preoperative PSA,Gleason score,number of puncture needles,tumor staging,intraoperative blood loss,operation time,positive margin rate,average postoperative hospital stay,urine control 3,6 and 12 months after operation,and complications.The psychological status of patients waiting for surgery was quantitatively assessed with anxiety and depression scale.Results: There were no statistical differences in the operation time,urine control 3,6 and 12 months after operation,intraoperative blood loss,positive margin rate and complications between the two groups(P>0.05).In the two groups of 105 patients,those who were lost to follow-up were excluded,and the mental state of 67 patients,There was no difference in the depression score between the two groups [(9.30±5.60)vs.(9.94±4.87),P=0.62],but IT≥4 group had higher anxiety score than IT<4 group [(9.64±4.94)vs.(14.41±3.47),P<0.001].Conclusion: The IT between prostate biopsy and radical prostatectomy does not affect the surgical difficulty or effect of surgery,but prolonged IT can aggravate the psychological anxiety of patients.