The Clinical Study Of Chronic Atrophic Gastritis(Spleen And Stomach Deficiency Type) Treated By Jianpiwenzhong Granule

Objective:The purpose of this study is to verify the clinical efficacy of Jianpi Wenzhong Granule in treating chronic atrophic gastritis(C AG),and to evaluate the clinical therapeutic effect of Jianpiwenzhong Granule on clinical symptoms,gastroscopic manifestations and pathological signs of patients in CAG treatment,to test the safety of the prescription in the treatment of patients.Methods: Eighty patients with CAG(spleen and stomach deficiency type)who met the inclusion criteria and did not meet the exclusion crite ria were randomly selected and randomly divided into two groups-the treatment group and the control group.The treatment group was given Jianpiwenzhong Granules(New Green Medicine Chinese Medicine Formula Granules,Sichuan New Green Pharmaceutical Tech nology Development Co.,Ltd.)Oral administration for 12 weeks,the control group was given Weifuchun(production of Hangzhou Huqing Yutang Pharmaceutical Factory;approval number : Chinese medicine quasi character Z20040003;0.36g×60s),4 tablets/time,3 times/day,oral for 12 weeks.After the end of treatment,the patients were followed up to evaluate the changes of clinical s ymptoms,gastroscopic manifestations and pathological si gns before and after treatment.The data were recorded and analyzed.The clinical efficacy and safety of the two groups were finally obtained.Results:1.In terms of TCM symptoms,the treatment group improved the symptoms of CAG(spleen and stomach deficiency type)in all TCM syndromes(P<0.05),and the treatment group was better than the control group in improving the symptoms offatigue and limb weakness.2.In the performance of gastroscope,the tre atment group did improve the atrophy under gastroscope(P<0.05)3.In terms of pathological manifestations,the treatment group improved the inflammation,atrophy and intestinal metaplasia of the gastric mucosa under pathological conditions(P<0.05);4.The treatment group was safe and had no adverse events;Conclusion: Jianpiwenzhong Granule can significantly improve the clinical symptoms of patients with CAG(spleen and stomach deficiency type),and improve the gastroscopic performance and pathological i nflammation,atrophy and intestinal metaplasia performance,and patients with no obvious adverse reactions during drug application,it is worthy of further clinical research and promot ion.