| ObjectiveThe purpose of this study is to collect and sort out the medical records of Professor Liu Xusheng’s treatment of diabetic kidney disease,and use data mining methods to analyze and summarize Professor Liu Xusheng’s academic thoughts and clinical experience in treating diabetic kidney disease,so that it has a good heritage and development.MethodsCollected 140 patients who met the exclusion criteria from January 1,2016 to December 31,2018 and were prescribed by Professor Liu Xusheng’s outpatient clinic,and prescribed a total of 226 medical records.Name,gender,age,and consultation After the basic information such as time,consultation,biochemical indicators,TCM staging,fourth diagnosis information,TCM syndromes,prescription medication and other information are standardized,they are entered into an Excel table to establish a medical case database for Professor Liu Xusheng’s diagnosis and treatment of DKD.Enter the medical record data into "Traditional Chinese Medicine Heritage Support Platform V2.5(TCMISS V2.5)",and use the "statistical report" module to analyze the basic information of the medical record,the four diagnosis information,the medicinal properties of the medicine,and the efficacy classification And frequency of drug doses,and use the "prescription analysis" and "medical case analysis" modules in the "data analysis" module to obtain the compatibility rules of traditional Chinese medicine,core combinations of traditional Chinese medicine,potential new prescriptions,etc.,and combine it with the clinical and academic characteristics of Professor Liu Xusheng.Analysis and summary of medication experience.ResultsThis study included 140 patients and collected a total of 226 medical records.The statistical analysis results are as follows:1.Basic information:Of the 140 patients included in this study,90 were males and 40 were females;the youngest was 26 years old,the oldest was 80 years old,and the largest number were 60-71 years old.2.Staging and four diagnosis information:Staging statistics of western medicine showed:16 cases of diabetic kidney disease stage Ⅲ,accounting for 7%;118 cases of stage Ⅳ,accounting for 52%;92 cases of stage V,accounting for 40%.Symptom statistics show that the higher frequency symptoms of DKD are fatigue,edema,nocturia,diarrhea,dry mouth,poor appetite,and backache.The most frequent pulses are thin pulses,followed by thin pulses,thin pulses and slippery pulses.The four qi of the drug have the most flatness;the five flavors are mainly sweet,bitter,and astringent;the top three returning meridian frequencies are the spleen,kidney,and liver meridians.3.Statistics on the frequency of drug use shows that the top 10 drugs with the highest frequency of use are Astragalus,Yam,Cuscuta,Glycyrrhiza,Salvia,Poria,Atractylodes,Centella Asiatica,Dogwood,Codonopsis;The top 3 drugs are classified as tonic medicine,Diuretic and dampness medicine,blood circulation and stasis medicine.4.The analysis of the prescription formula showed that there were 22 core drug combinations and 14 strong associations.There are 11 new party combinations.ConclusionProfessor Liu Xusheng has unique insights and rich clinical experience in the treatment of diabetic kidney disease with traditional Chinese medicine.This study uses the traditional Chinese medicine inheritance auxiliary platform to analyze and analyze Professor Liu Xusheng’s treatment of DKD medical records.Sexual experience.Professor Liu believes that the pathogenesis of diabetic kidney disease is mainly based on deficiency,which is based on the evidence that the deficiency is true and the reality is mixed.The "virtual" ones are mostly qi deficiency,spleen deficiency,and kidney yang deficiency,and the "real" ones are mostly wet,stasis,and phlegm.Treatment is mainly based on tonic deficiency,with special emphasis on tonifying the spleen and kidney,and at the same time,syndrome differentiation and treatment are given.The use of data mining methods enables Professor Liu Xusheng’s experience in the treatment of diabetic kidney disease to be better inherited and promoted,so that it originates from the clinic and is superior to the clinic,with a view to returning to guide the clinic. |