| Objective By retrospective survey study on cases after treating early threatened abortion continue to pregnancy and cases without threatened abortion medical history,comparing the difference between the both pregnancy outcome,provide data support for the safety and efficacy of treating early threatened abortion by traditional Chinese medicine.Methods Randomly selected 456 cases whose gestational weeks less than 12 weeks without other risk factors after treating early threatened abortion by traditional Chinese medicine continue to pregnancy in ward and outpatient of Hangzhou TCM hospital from January 2013 to June 2014 as the group of spuc medical history,and randomly selected 450 cases who without threatened abortion medical history in the same hospital at the same time as the control group.By looking at the ward case,a pair of side visit or telephone inquiries,collect medical data,including:1.The scheme of preventing early threatened abortion.2.Prenatal screening results:21-three body syndrome,18-three body syndrome and neural tube defects;prenatal diagnosis results,including an amnio,three-dimensional ultrasound,etc.3.Special diseases during pregnant time include pregnancy gestational hypertension,intrahepatic cholestasis of pregnancy,gestational diabetes mellitus and incidence and gestational anemia,liver and kidney dysfunction,hyperlipidemia,etc.Abnormal of amniotic fluid volume or the umbilical cordincludehydramnios,oligohydramnios,umbilical cord entanglement,abnormal umbilical cord length.The placenta and fetal membrane abnormalities include placenta previa,premature rupture of membranes,placental abruption,placenta adhesion,fetal membrane residues.Intrapartum complications include fetal intrauterine distress,postpartum hemorrhage,amniotic fluid embolism,uterine rupture.Other data include weight gain during pregnancy,childbirth,gestational age,abnormal position,delivery mode.4.Neonatal adverse outcomes include death,newborn asphyxia of newborn babies,congenital malformations,hemangioma,finger(toe),the term low birth weight,macrosomia,hypospadias,height and weight of birth,and the status of children’s physical development.Compare two groups of data and analysis,summarize the influence of pregnant outcome after treating early threatened abortion by traditional Chinese medicine.Results 1.The scheme of preventing early threatened abortion:32 cases treated only by Chinese traditional medicine,424 cases treated by combining Chinese traditional medicine and Western medicine.2.Comparing the results of both the two groups of prenatal screening and prenatal diagnosis were no significant differences(p>0.05).3.Comparing two groups of endemic disease incidence of pregnancy,amount and incidence of abnormal umbilical cord and placenta previa,placental abruption,the incidence of placenta adhesion,fetal membrane residues,intrapartum complications had no significant difference(p>0.05);the incidence ofremature rupture of membranes in the group of spuc medical history was higher than the control group,and had significant differences(p<0.05);the incidence of preterm birth in the group of spuc medical history was higher than the control group,and had significant differences(p<0.05).4.Comparing neonatal outcome,the height and weight of newborn babies,children’s physical development between the two groups had no significant differences(p>0.05).Conclusion 1.Treating early threatened abortion will not increase the rate of prenatal screening high-risk,abnormal rate of prenatal diagnosis.2.Treating early threatened abortion will not increase the rate of gestational hypertension,gestational diabetes,intrahepatic cholestasis during pregnancy and gestational anemia,liver and kidney dysfunction during pregnancy,gestational hyperlipidemia.3.Treating early threatened abortion will not increase the rate of hydramnios,oligohydramnios,umbilical cord entanglement,umbilical cord twist,the umbilical cord too short and placenta previa,placental abruption or placenta adhesion.4.Treating early threatened abortion will not influence the choice of delivery mode,will not increase the rate of postpartum hemorrhage,amniotic fluid embolism,uterine rupture.5.Treating early threatened abortion will not increase the rate of neonatal adverse outcomes and had nobad effects on the height and weight of the newborn.6.After treating early threatened abortion birthed children’s physique growth is in the normal range.7.The incidence ofremature rupture of membranes in the group of spuc medical history was higher,so that 28~36+6 weeks of cases increased,consider to the history of early threatened abortion. |