| Objective: In recent years,the prevalence of type 2 diabetes(Type 2 diabetes mellitus,T2DM)has increased rapidly in China,and its universality has attracted people’s attention.Although T2DM occurs in individuals,it has already threatened social stability.Overweight,obesity,and sleep disorders have gradually developed into major public health problems that seriously affect the physical and mental health of people all over the world.However,no unanimous conclusions have been drawn on the impact of T2DM.Therefore,this study adopts a cross-sectional survey method to conduct an investigation in a city in Liaoning Province.The purpose is to obtain the current prevalence and epidemiological characteristics of T2DM in residents over 35 years old in a city in Liaoning Province,and to explore the overweight,Risk factors such as obesity and sleep disorders provide a theoretical basis for its prevention and effective control of the occurrence of T2DM and the formulation of measures.Methods: This study adopts a cross-sectional research design and applies the stratified cluster sampling method to sample the study population in a city in Liaoning Province from June to August 2019.At the survey site,trained investigators used face-to-face conversations to interview participants.The research subjects collected relevant information.In this survey,a total of 4,774 questionnaires were distributed and 4,695 were recovered.The final effective response rate of the questionnaire was98.3%.The prevalence of overweight,obesity,sleep disorders,and T2DM among residents over 35 years of age was obtained through questionnaires and physical examinations.Multivariate logistic regression analysis was used to analyze the association between overweight,obesity,sleep disturbance and T2DM,calculate odds ratio(OR value)and 95% confidence interval(95% CI),and perform sensitivity analysis on the stability of the results.Results:1.A total of 4066 residents over 35 years of age were included in this study.Among all the study subjects,there were 1481 males,accounting for 36.42%,and 2585 females,accounting for 63.58%,with an average age of 58.9 years;the prevalence rate of the total population diagnosed by fasting blood glucose was 11.98%,the prevalence of T2DM in the total population diagnosed by fasting blood glucose was11.98%,and the prevalence of women(12.92%)was higher than that of men(10.22%)(P=0.014).In the total population,the levels of survey subjects’ BMI,WC,WHR,and WHt R are 24.69±3.73kg/m2,84.04±9.99 cm,0.89±0.08,0.52±0.06;FPG is 5.96±1.87mmol/L.Women have a higher risk of T2DM than men(OR = 1.29,95% CI:1.05-1.58);people over 60 years of age have a 1.53 times higher risk of T2DM compared with younger people.In the total population,the prevalence of human T2DM in abdominal obesity judged by WC,WHR and WHt R was higher than that of the normal group(P<0.001).At the same time,with the continuous increase of BMI,the prevalence of adult T2DM also increases(P-trend=0.001);in the total population,the prevalence rate of systemic obesity is 17.78%,and the prevalence rate of male systemic obesity is 14.79.%,the prevalence of systemic obesity in women was19.50%;among the surveyed population,the prevalence of overweight was 38.49%,and the prevalence of overweight in men(34.74%)was lower than that in women(38.92%);The rate of abdominal obesity classified by WC is 42.38% in the total population;the rate of abdominal obesity defined by WHR is 42.38% in the total population;in the population of this study,the rate of abdominal obesity defined by WHt R increases with the age of the survey subjects2.The prevalence of sleep disorders in the total population is 20.17%;the prevalence of sleep disorders in men is 14.25%,and the prevalence of sleep disorders in women is 23.56%;3.In the univariate model,systemic Both overweight and obesity are risk factors for T2DM,and with the increase of BMI level,the risk also increases(OR = 1.44,95%CI: 1.16-1.78,OR = 1.47,95% CI: 1.13-1.91).The abdominal obesity classified by WC,WHR,and WHt R all have a significant effect on T2DM,and the OR value is greater than 2.The model adjusted by age and multi-factors shows that compared with the other three indicators,the abdominal obesity defined by WHR has the closest relationship with T2DM and the most significant impact on the normal population.The risk of T2DM is 2.5 times,its OR value and 95% CI are 2.52(1.98-3.20);when different obesity indicators are used as continuous variables,each increase in standard deviation has a significant correlation with T2DM.After adjustment by multi-factor model,BMI,The OR value and 95% CI of the risk of T2DM in WC,WHR and WHt R were 1.22(1.10-1.35),1.44(1.30-1.60),1.45(1.30-1.61)and 1.48(1.33-1.64),respectively;in the male population,There is a positive correlation between the four obesity indicators and T2DM.After age stratification,it is found that among people over 60 years old,there is a strong correlation between the four obesity indicators and adult T2DM,most of which have an OR value greater than 2.4.In this survey;regardless of the single factor,age-adjusted and multi-factor adjustment models,it was shown that the total score of sleep disturbance and PSQI has nothing to do with the risk of adult T2DM(P>0.05);the interaction between different obesity indicators and sleep disturbance It is not statistically significant with adult T2DM(all P interaction> 0.05).Conclusion: The prevalence of T2DM is different in people of different ages,and the prevalence of T2DM in women is higher than that in men.The prevalence of obesity and overweight is higher than that of other regions,and the prevalence of sleep disorders among young people is lower than that of the elderly.The four obesity indicators BMI,WC,WHR and WHt R all increase the risk of T2DM,and with the continuous increase of BMI,the prevalence of T2DM shows an upward trend.Whether in men or women,the correlation between WHR and T2DM prevalence is the strongest.Although there is no overall association between sleep disturbance and T2DM,in the nocturnal sleep disturbance dimension score,when the lowest score is used as a reference,the highest score is related to the increased risk of T2DM,and as the score on this dimension increases,T2DM occurs The increasing trend of risk has obvious statistical significance.The interaction between overweight,obesity and sleep disorders is not related to the risk of T2DM.Therefore,further epidemiological investigations are needed in the future to explore the relationship between the interaction between the two and T2DM,as well as to study their role in the pathogenesis of T2DM. |
PDF Full Text Request