Difference Analysis Of Late-onset Hypogonadism In Middle-aged And Elderly Men Between Urban And Rural Population

Objectives:1 To study the differences of ADAM questionnaire and AMS table in screening middle-aged and elderly male hypogonadism patients in different age groups and different living environments。2 The difference in the incidence and severity of erectile dysfunction symptoms in different age groups and people from different living environments.3 Differences in serum total testosterone(TT),S sex hormone binding globulin(SHBG),Free testosterone(CFT)and bioactive testosterone(Bio-T)in different age groups and people from different living environments.Methods:A total of 200 middle-aged and elderly men aged 40-79 living in urban and rural areas were selected from the physical examination center of our hospital from June2020 to December 2020,and divided into four age groups according to 40-49 years old,50-59 years old,60-69 years old,and 70-79 years old.Three questionnaires were conducted for them.Serum levels of albumin(ABL)、TT and SHBG were determined,including ADAM,AMS and IIEF-5.CFT and Bio-T were calculated by Vermeulen formula.Results:The positive rates of ADAM and AMS in 200 middle-aged and elderly men were57.5% and 45.5%,respectively.With the increase of age,the positive rates of LOH screening also increased.The positive rates of ADAM and AMS screening in the urban group were higher than those in the rural group at the age of 50 to 59 years,and the difference was statistically significant.The total prevalence of ED in 200 middle-aged and elderly residents was69.0%.Compared with the 70 to 79 years old group,the incidence of ED in the 40 to49,50 to 59 and 60 to 69 years old groups was statistically different(P < 0.05).Compared with the 60 to 69 years old group,the incidence of ED in the 40 to 49 years old group was statistically significant(P < 0.05).In the 200 test reports collected,the mean TT value was 458.24±143.29ng/d L,the mean SHBG value was 33.14±10.80nmol/L,the mean CFT value was10.01±4.24ng/d L,and the mean CBIO-T value was 232.70±98.44ng/d L.The values of SHBG increased with age,The TT,SHBG,CFT and horizontal Bio-T levels in different age groups of LOH positive patients in urban and rural areas were compared based on the positive results of Adam questionnaire screening as LOH patients.The CFT and Bio-T levels of LOH positive patients in urban areas were lower than those in rural areas from 50 to 59 years old.The difference was statistically significant(P <0.05).Conclusion:1.It is suggested to use the ADAM questionnaire and AMS scale to preliminarily screen LOH,and the ADAM questionnaire has a higher positive rate of LOH than the AMS scale.2.The prevalence of LOH was lower in the rural group than in the urban group,and the levels of CFT and Bio-T were higher in the rural group than in the urban group.But there was no significant difference in the incidence of ED between the two groups。3.SHBG increased with age,CFT and Bio-T decreased with age,and TT had no correlation with age.