Study On Pollution Characteristics And Bioaccessibility Of Short-chain Chlorinated Paraffin And Phthalates In Student Supplies

Different types of toxic and harmful compounds may be added to consumer products.These compounds can be released into the environment in the form of gas and particles in the daily use of consumer products,and are easily entered into the human body through different ways such as the respiratory tract,mouth and skin.Health poses a potential threat.Most risk assessments for contaminants in consumer products are based on the total concentration of compounds,which may lead to overestimation of risks.It is more accurate to use bioaccessibility parts for risk assessment.This paper investigates the pollution characteristics of short-chain chlorinated paraffins(SCCPs)in schoolbag samples and phthalates(PAEs)in rubber samples.To assess the possible migration process,a simulated lung tissue fluid replacement technique was used to assess the bioaccessibility of particulate chemicals released in consumer products after inhalation to provide scientific data for corresponding human exposure assessment and health risks.The main research results of this paper are as follows:1. This paper studies the pollution characteristics of phthalate esters in short-chain chlorinated paraffin and rubber samples in schoolbag samples.The results showed that the presence of SCCPs was found in 86.20%of the schoolbag samples,with a mass score ranging from 0.06-1.48%.The SCCPs carbon homologues in the schoolbag are mainly C₁₀ and C₁₂,and the chlorine homologues are mainly Cl₇ and Cl₈.Principal component analysis showed that the short-chain chlorinated paraffin in the schoolbag was probably from industrial products CP-42and CP-52b.DEHP,DIBP,DBP and DINP were detected in the rubber samples,with a mass fraction between 0.002-15.55%,and 42.60%of the samples contained PAEs with a mass fraction exceeding 0.1%.2. Use an in vitro simulation device to study the bioaccessibility of schoolbag particles.The results showed that the bioaccessibility scores of short-chain chlorinated paraffin in schoolbags ranged from 0.20%to 25.95%.The skin material is polyurethane synthetic leather with the highest bioaccessibility score,which is 12.25%(ALF)and 25.94%(MGS)in the two lung fluids,followed by the particulate matter samples containing polyurethane components are 4.28%(ALF)and 4.21%(MGS).The C₁₀ and C₁₁ components in the carbon homologue are in Student Supplies the easiest to migrate into the lung fluid,and the Cl₆and Cl₇ components in the chlorine homologue are the easiest to migrate into the lung fluid.Risk exposure assessment results show that the maximum daily exposure of SCCPs in children and adults is 59.00 and 21.50?g/kg-bw·day.At the highest concentration levels,both children and adults are faced with a higher risk of carcinogenesis;using bioaccessibility After the correction of inhalation exposure,the human inhalation exposure was significantly reduced.3. Use Tenax to carry out the adsorption test for PAEs in the simulated lung fluid,and use the in vitro simulation device to study the bioaccessibility of the rubber particles.The results showed that Tenax reached the maximum adsorption capacity of 5.02-35.10%(ALF)and 4.41-34.98%(MGS)for most PAEs within 24 h,and decreased to 1.09-25.16%(ALF)and 1.64-11.35%(MGS).Among the rubber samples,DBP and DIBP had the highest bioavailability scores of 8.20-86.07%and 15.35-85.91%,respectively,and DEHP bioaccessibility scores were0.02-0.64%;DINP was not detected in lung fluid.The risk assessment results show that the maximum daily exposure of PAEs in children and adults is 573.00 and 83.50?g/kg-bw·day.At the maximum concentration,both children and adults face higher non-carcinogenic and carcinogenic risks.After using bioavailability to correct the inhalation exposure,the human inhalation exposure was significantly reduced.