| Wounds can be caused by a number of reasons including trauma, surgical procedures, or burns. Current would dressings are frequently made of hydrophilic materials, causing them to adhere to exposed wound tissue and exudate, resulting in damage to the healing wound and pain upon dressing changes. This project designed and tested a novel non-adhesive wound dressing that does not adhere to the underlying wound tissue upon removal, and also discourages the growth of bacterial biofilm on its surface, while still allowing for exudate absorbance. Cellular adhesion tests were conducted with both eukaryotic and prokaryotic cells, comparing the novel wound dressings to commercially-available dressings indicated for use on burn wounds. Results showed that the novel dressings adhered to less human fibroblast cells and P. aeruginosa biofilm after 3 days. An effective non-adhesive wound dressing, with antimicrobial abilities, would significantly benefit both the patient and the healthcare system as a whole. |
