Solid phase synthesis of hybrid peptides containing synthetic beta-turn prosthetic units
Posted on:1991-12-06
Degree:Ph.D
Type:Thesis
University:University of Illinois at Chicago
Candidate:Bertenshaw, Stephen Randolph
Full Text:PDF
GTID:2471390017951136
Subject:Chemistry
Abstract/Summary:
study of the importance of ;The turn mimetics were found to be rather amenable to incorporation on their carboxy terminus. The continuation of the synthesis from the amino-terminus however proved to be quite challenging. Most of the synthetic effort expended was directed towards achieving this goal of incorporation on the amino-terminus. For this purpose three separate ;Ultimately the turn mimetic was fully incorporable and was used to demonstrate that...