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Evaluation of brain hypoxia with radiolabeled iodoazomycin arabinoside (IAZA) in the gerbil stroke model

Posted on:1998-05-03Degree:M.ScType:Thesis
University:University of Alberta (Canada)Candidate:Liu, HuiFull Text:PDF
GTID:2464390014475631Subject:Health Sciences
Abstract/Summary:
Radioiodinated iodoazomycin arabinoside (IAZA) has been synthesized as a non-invasive marker for tumor hypoxia and has shown hypoxia-selective binding in variety of ischemic tissues. In the present study, a Mongolian gerbil stroke model is used to investigate the potential of IAZA in detecting brain ischemia.;In vivo biodistribution of ;The above results are interpreted to indicate that...
Keywords/Search Tags:Iodoazomycin arabinoside, Gerbil stroke model
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