Effect of low and high GI carbohydrate on blood glucose and food intake at two and four hours in young men

The hypothesis tested was that preloads of high GI carbohydrate (glucose) compared with low GI carbohydrate (high amylose cornstarch) promote less satiety and greater food intake at two and four hours, and that these responses are associated with their effects on blood glucose. Liquid and solid preloads (75 grams) were administered to young men, and blood glucose, appetite and food intake were measured. Glucose produced a larger glycemic response than amylose. At two hours, but not at four, glucose reduced food intake and blood glucose concentration was inversely related to food intake. None of the treatments reduced food intake at four hours. Thus, in the amount provided, high GI carbohydrate compared with low GI carbohydrate, promoted greater satiety and less food intake at two hours, but was similar at four hours. These results could not be attributed to the effects of the treatments on blood glucose.