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Evaluation of autologous platelet gel in breast reduction surgery: A randomized controlled trial

Posted on:2006-08-11Degree:M.ScType:Thesis
University:University of Alberta (Canada)Candidate:Anzarut, Alexander DavidFull Text:PDF
GTID:2454390005999575Subject:Health Sciences
Abstract/Summary:
Introduction. Completely autologous platelet gel (CAPG) is designed to decrease the rate of post-operative seromas and hematomas. We hypothesized the application of CAPG would reduce post-operative drainage and complications, while improving wound healing, compared to standard care in bilateral reduction mammoplasty (BRM).; Methods. We conducted a within-patient, randomized, patient and evaluator-blinded, controlled trial in 111 patients undergoing BRM. CAPG was applied to either the right or left breast. The primary outcome was the difference in wound drainage. Secondary outcomes included pain and wound healing. Assessments of wound healing included size of any open areas, clinical scar assessments, scar pliability, and scar erythema.; Results. No statistically significant differences in the drainage, level of pain, size of open areas, clinical appearance, degree of pliability, or erythema were noted.; Conclusions. Our results do not support the use of CAPG in BRM.
Keywords/Search Tags:CAPG
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