| Scope and Method of Study. Near-infrared diffuse optical tomography (NIR-DOT) can provide high intrinsic contrast images of the human tissue. To imaging internal organ like prostate, it is necessary to develop endoscopic mode NIR-DOT system. Furthermore, due to the different optical diffuse coefficients of the oxygenated and deoxygenated hemoglobin in the near infrared band, the total hemoglobin concentration (HbT) and the oxygen saturation of the blood (StO2) can be quantitatively estimated by implementing dual-spectral detection into endoscopic mode near-infrared diffuse optical tomography system.;Findings and Conclusions. In this project, the phantom study and the blood test were performed; the preliminary results showed that by implementing dual-spectral detection into the endoscopic probe, the near-infrared optical tomography imaging system could reveal the absorption coefficient changes of the heterogeneous objects and the blood StO2 changes. |
