| ObjectiveThis study systematically evaluated the effectiveness and safety of the method of nourishing Qi and blood in the treatment of postpartum rheumatism.MethodRetrieval strategyThe randomized controlled trial literatures about the treatment of postpartum rheumatism with the method of nourishing Qi and blood was collected from the CNKI,CBMdisc,Wanfang Data,VIP database,etc.Based on the principles and methods of clinical epidemiological literature evaluation,the quality evaluation and information collection table of the clinical literatures on the treatment of postpartum rheumatism with the method of nourishing Qi and blood were formulated,and the qualified ones were selected.In this study,according to the commonly used scoring standards of the literature quality of RCTs,the quality of the clinical research on the treatment of postpartum rheumatism with the method of nourishing Qi and blood was evaluated,and the data was analyzed with the Review Manager 5.3 software after the data was extracted.Inclusion criteria:We collected all the RCTs of postpartum rheumatism intervention,which were compared with placebo,western medicine and blank control.Blind and non blind studies were included.Exclusion criteria:Exclude the studies that the intervention in the experimental group or the control group was unreasonable,as was the case in the non parallel control study.Data collection and analysis:Two evaluators independently extract data and evaluate the quality of each other's jurisprudenceResult1.A total of 1457 documents were retrieved and finally included in 22 RCTs,all of which were low-quality studies.18 RCTs' experimental groups were treated with pure Chinese medicine,including 15 RCTs with the intervention of traditional Chinese medicine for nourishing Qi and blood VS traditional Chinese medicine not for nourishing Qi and blood,2 RCTs of traditional Chinese medicine for nourishing Qi and blood VS non drug therapy,and 2 of traditional Chinese medicine for nourishing Qi and blood VS western medicine;4 RCTs'experimental groups were treated with traditional Chinese medicine+external treatment,including 3 RCTs with the intervention of traditional Chinese medicine for nourishing Qi and blood+external treatment of western medicine VS western medicine;and 1 RCT of traditional Chinese medicine for nourishing Qi and blood+External treatment of TCM VS western medicine.There is no description of random assignment and concealment in any literature,all the blind methods used in the literatures have problems in varying degrees,5 literatures describe the cases of withdrawal,loss of visit and rejection in detail,7 literatures describe the number and specific situation of adverse reactions in detail.2.Among the 22 RCTs included,21 RCTs'total efficiencies were included in the meta-analysis.There were 17 RCTs of intervention with traditional Chinese medicine for nourishing Qi and blood,with RR value of 1.35 and 95%confidence interval of[1.23,1.50].The difference was statistically significant,indicating that the therapeutic effect of the method of nourishing Qi and blood on postpartum rheumatism was better than that of non Qi and blood nourishing;there were 4 RCTs of intervention with traditional Chinese medicine of nourishing Qi and blood+external treatment,with RR value of 1.41 and 95%confidence interval of[0.93,2.15],the difference is not statistically significant,which shows that the therapeutic effect of the traditional Chinese medicine for nourishing Qi and blood+external treatment is not significant.ConclusionThe results of this systematic evaluation study show that the method of nourishing Qi and blood is effective in the treatment of postpartum rheumatism,and its effect is higher than that of traditional Chinese medicine not for nourishing Qi and blood;The treatment method that traditional Chinese medicine for nourishing Qi and blood+external treatment is effective in the treatment of postpartum rheumatism,and its effect is better than that of western medicine or external treatment of traditional Chinese medicine.It provides evidence-based medicine reference for the treatment of postpartum rheumatism by traditional Chinese medicine for nourishing Qi and blood,and fills in the blank of literature research,which has certain reference significance for the follow-up research.However,due to the low quality of literature,more large samples and multi centers of well-designed randomized controlled trials are needed to provide scientific basis for clinical decision-making. |
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