Based On Data Mining To Explore The Rules Of Traditional Chinese Medicine In The Treatment Of Diabetic Peripheral Neuropathy

Purpose : Through the analysis of traditional Chinese medicine internal and methods for the treatment of diabetic peripheral neuropathy related literature,summarizes the clinical treatment of diabetic peripheral neuropathy in general characteristics,including its influence on nerve conduction type,often witness,summarized the treatment as well as to sent the clinical,summed up the potential new prescription medication rule and Chinese medicine,in order to better guide clinical and research use.Material and method:1.Searched related literatures on the internal administration of traditional Chinese medicine for the treatment of diabetic peripheral neuropathy from January 1999 to mid-december 2019 in databases of China national knowledge network and Wanfang,and carefully read,excluded and included the retrieved literatures,and established the original database.2.Sorted out the Chinese medicine prescriptions and drug compositions that met the inclusion criteria.3.Relevant software Excel2010,SPSS26.0,and SPSS Modeler18.0 were used to conduct statistics on the medication frequency and frequency of the drugs involved in the literature,and data analysis was conducted on the sexual taste,regression,drugs,species clustering,and drug correlation of high-frequency drugs.Results:1.Frequency and frequency statistics: among the 101 included literatures conforming to the research standards,126 traditional Chinese medicines were involved,with a total frequency of 1071 times and an average frequency of 8.5 times.There were 30 drugs above the average frequency.Among all the high-frequency drugs,astragalus had the highest frequency,appearing 81 times,accounting for 80.20% in all the TCM compounds and 7.56% in the total frequency,followed by angelica,chuanxiong,earthworm,caulis spatholobus and safflower.2.Statistics of the property,taste,warp and drug category: the 126 traditional Chinese medicines were comprehensively counted,and it was found that the temperature was the most frequently used in the property,which was flat,slightly cold,lukewarm,cold and cool in order.No hot drugs were found.In the drug taste statistics,the highest frequency is the sweet taste,according to the order of high and low is spicy,bitter,sour,salty,slightly bitter,astringent.The liver meridian has the highest frequency,and the spleen meridian,heart meridian,lung meridian,kidney meridian and stomach meridian are in the order of high and low.In the drug category of statistics is the highest frequency of the circulation of blood regulating drugs,followed by blood tonic,qi tonic,heat cooling blood drugs.3.Cluster prescription and drug combination statistics: 5 groups of cluster prescription and 12 groups of TCM prescription were obtained.Conclusion:1.Through clinical data analysis,astragalus membranaceus,angelica sinensis,ligusticum chuanxiong,earthworm,caulis spatholipis,safflower,cassia twig,salvia miltiorrhiza,achyranthes bidentata and peach kernel are commonly used clinical drugs for the treatment of DPN.2.The selected drugs have the main properties of warm and flat,the main taste of gan and xin,and the main use of blood-activating and regulating drugs,blood-enriching drugs,and qi-tonifying drugs.The drugs are mainly liver,spleen and heart meridians.3.The basic clinical drug selection methods for the treatment of DPN patients are qi supplementing,blood circulation and collateralization.