Research On The Medication Rules Of Traditional Chinese Medicine For Prevention And Treatment Of Aura Of Stroke Based On Data Mining

Purpose:To explore the rules of TCM and the treatment of Chinese medicine for the prevention and treatment of stroke precursor,to provide reference for clinical treatment.Material and method:By using keyword search method,we searched the clinical literatures on the treatment of stroke precursor with traditional Chinese medicine and combination of traditional Chinese and western medicine in CNKI,Wanfang Database,Chongqing Weipu Database,SpringerLink and ScienceDirect from January 2010 to January 2019.We standardized the selected medicines,prescriptions and terminology in the literature,extracted the relevant information such as title,publication date,prescriptions and traditional Chinese medicines,and used Excle software to conduct frequency analysis and SPSS22.0software was used for cluster analysis,visual analysis of clustering results was carried out by Gephi0.9.2 software.Results:1.This study included 92 articles,112 prescriptions of traditional Chinese medicine,involving 136 kinds of traditional Chinese medicine.2.The total frequency of 136 kinds of traditional Chinese medicine was 1219 times,and the average frequency of use was 9 times.There are 37 kinds of traditional Chinese medicine with frequency ? 9,accounting for 27.20% of the total number of traditional Chinese medicine,and the cumulative frequency can reach 79%.It is suggested that the application of traditional Chinese medicine is mainly focused on the use of traditional Chinese medicine with frequency ? 9.The first 10 kinds of traditional Chinese medicine with the most frequency were Ligusticum chuanxiong,Glycyrrhiza uralensis Fisch,Dilong,safflower,Gastrodia elata,Angelica sinensis,Astragalus membranaceus,Radix Paeoniae Rubra,Radix Salviae Miltiorrhiza and Achyranthes bidentata.3.The first three types of traditional Chinese medicine were as follows: Huoxue Huayu drugs(frequency 297 times,frequency 24.36%),tonifying deficiency drugs(frequency 296 times,frequency 24.28%),calming liver and relieving wind medicine(frequency 189 times,frequency 15.50%).Among the drugs of tonifying deficiency,the drugs of tonifying qi accounted for 56% of the drugs,followed by the drugs of replenishing blood,tonifying yin and yang,accounting for 28%,12% and 4%,respectively.4.The frequency and frequency of traditional Chinese medicine four qi were warm(366 times,frequency 30.02%),flatness(333 times,27.36%)and slight cold(203times,16.65%).5.The frequency and frequency of traditional Chinese medicine(TCM)were sweet(548 times,frequency 30.82%),bitter taste(519 times,29.19%)and pungent flavor(426 times,23.96%).6.The frequency and frequency of traditional Chinese medicine were 799 times(27.08%),467 times(15.83%)and 458 times(15.53%)respectively.7.Cluster analysis showed that the main combination of traditional Chinese medicine for the treatment of apoplectic omen was as follows:(1)three types: invigorating qi,activating blood circulation,searching wind and dredging collaterals,invigorating spleen,dispelling dampness,eliminating phlegm and opening orifice,calming the liver and extinguishing wind,nourishing yin and clearing away heat;(2)four types: invigorating qi and activating blood circulation,searching wind and dredging collaterals,invigorating spleen,dispelling dampness,eliminating phlegm and opening orifice,calming liver and extinguishing wind,nourishing yin and clearing away heat;(3)six types: invigorating qi and activating blood circulation,searching wind and dredging collaterals,invigorating spleen and dispelling dampness,eliminating phlegm and opening orifice,calming liver and extinguishing wind,nourishing yin and clearing away heat.Conclusion:1.The first 10 kinds of traditional Chinese medicine are: Chuanxiong,Glycyrrhiza uralensis Fisch,Dilong,safflower,Gastrodia elata,Angelica sinensis,Astragalus membranaceus,Radix Paeoniae Rubra,Radix Salvia miltiorrhiza,Achyranthes bidentata,which can be used as a reference for clinical drug selection.2.The commonly used drugs for the treatment of apoplexy threatened by promoting blood circulation and removing blood stasis were the first,the medicine of tonifying deficiency was the second,and the medicine of calming liver and relieving wind was the third.3.Sexual temperature,taste sweet,return to the liver meridian is the medicinal characteristic of treating apoplexy precursor medicine.4.There are three main groups of drugs for the treatment of apoplexy precursors,including three categories,four categories and six main clusters,but the clustering of six categories is more appropriate to clinical practice,and is more convenient for clinical addition and subtraction and flexible application.In order to improve the curative effect,the combination of traditional Chinese medicine,which is closely related to each other,can be selected for clinical use.5.According to the method of drug measurement,the common methods for the treatment of apoplectic omen are: invigorating qi and activating blood circulation,calming liver and relaxing wind,searching wind and dredging collaterals,eliminating phlegm and opening orifice,invigorating spleen and dispelling dampness,nourishing yin and clearing heat method.6.The combination of drugs in this study has a certain correlation with the common single traditional Chinese medicine,common drugs and traditional Chinese medicine,and all of them are consistent with the pathogenesis,indicating that the results of the study have clinical reference value.