Research On The Six Channels Of Cough Variant Asthma

Cough variant asthma(CVA)is a common disease in respiratory diseases in recent years,it is a special type of asthma with chronic cough as the main clinical manifestation.CVA is the most common cause of chronic cough,accounting for about one-third of the causes of chronic cough,and its incidence has gradually increased in recent years.CVA has similar pathophysiological characteristics as asthma,including airway hyperresponsiveness,airway eosinophilic inflammation and airway remodeling.Currently,Western medicine is mainly based on inhaled corticosteroid(ICS)and bronchodilator,although it can effectively control the symptoms,it inevitably has problems such as side effects after long-term medication and easy recurrence after stopping the drug.Traditional Chinese medicine pays attention to the overall concept,emphasizes the treatment of the disease,treats both the symptoms and the root causes,and the flexibility of clinical treatment.It has accumulated rich experience in syndrome differentiation and treatment of cough,stagnation and other disease syndrome,which can provide valuable reference for the diagnosis and treatment of CVA,and many clinical practices also prove that Chinese medicine has a definite curative effect on prevention and treatment of CVA.At present,the traditional Chinese medicine treatment of CVA is mainly based on syndrome differentiation of viscera,and there are few studies on the application of six-meridian syndrome differentiation.Since the establishment of the six-meridian syndrome differentiation by Zhang Zhongjing,many doctors in the later generations have used this as a basis to prove that the six-meridian syndrome differentiation have the characteristics of clear syndrome differentiation and reliable curative effect in the treatment of diseases through clinical practice.Therefore,this topic focuses on the six-meridian syndrome differentiation research of CVA,explores the distribution law of CVA's six-meridian syndromes,and provides a reference for CVA clinical syndrome differentiation.Objective:Through the analysis and statistics of the clinical data of 122 patients with CVA,according to the six-meridian syndrome differentiation of classification and discussion,the characteristics of the six-dimensional syndrome classification of CVA was summarized,which provided a reference for clinical syndrome differentiation.Methods:Through analysis and statistics of the four diagnostic information of patients with CVA,the six-meridian syndrome differentiation were analyzed,and SPSS 23.0 was used to describe the links between gender,age,course of disease,disease season,degree of cough,nature of cough and six-meridian syndromes.Results:In CVA patients,there are more women than men,the ratio of man to woman is 1:2.59.Their age is from 4-75 years old,and the young patients account for 51.2%.The disease course?8weeks accounting for 67.2%,and the disease season is the most in autumn,accounting for 44.3%.The most common complication is Allergic rhinitis which accounts for 35.2%.In the factors that induce or aggravate cough,cold is the most,accounting for 46.7%.The frequency of cough is>97%,moderate cough accounting for 51.6%,and 71.3%of patients shows cough with phlegm,among which the less amount of sputum accounts for 34.3%.The common clinical tongues are:pale red tongue(15.6%),dark red tongue(13.9%),red tongue(12.3%),and the common tongue coatings are:thin white fur(32.8%),thin yellow fur(14.8%),thin white greasy fur(9.8%),yellow greasy fur(9.8%),and the common pulses are:thin string pulse(27.9%),thin slippery pulse(16.4%),string slippery pulse(15.6%).There are 22 cases(18.0%)with single meridian disease,of which Shaoyang disease is the most,accounting for 7.4%,58 cases(47.5%)with two meridian disease,and the combination of Shaoyang disease Yangming disease was the most common,accounting for 19.7%.There were 42 cases(34.4%)with three or more meridian disease,of which the combination of Taiyang disease,Shaoyang disease and Yangming disease was the most common,accounting for 11.5%,the most common single meridian disease after splitting was Shaoyang disease(78.7%).After that,it was Yangming disease(57.4%),Taiyang disease(49.2%),and Taiyin disease(32.8%).After non-parametric chi-square test,the distribution of the six-meridian syndromes of CVA is statistically significant.Conclusion:1.CVA patients are mainly young patients,more women than men,it can occur all year round,but more in autumn.CVA mainly manifests as chronic cough,mostly dry cough or cough and less cough,cough is mostly light and moderate,The main factors that induce or aggravate cough are cold,air odor irritation,cold,and wind.2.The six-meridian syndrome differentiation of CVA is independent of the patient's gender,age,disease course,disease season,cough nature and extent.3.CVA patients can be seen in the six-meridian diseases,mainly in meridians combination.4.The incidence of CVA is mainly due to Yang meridian disease,and Shaoyang and its combined diseases are the most common.In the Yin meridian disease,Taiyin and its combined diseases are the most common,Shaoyin disease and Jueyin disease are less involved,which indicates the disease position is relatively superficial.5.CVA patients with a disease course<8weeks are more common with the combination of Shaoyang disease and Taiyang disease,and those with a disease course ?8weeks are more common with the combination of Shaoyang diseases and Yangming diseases.