| Objective:To find an effective method for clinical treatment of insomnia by observing the clinical efficacy of Shumian capsule combined with oxazepam tablets in treating climacteric insomnia of liver depression and mental distress.Methods:Cases were collected in the outpatient department of Anjia Hospital in Huairou City.Beijing.From August 2016 to August 2017.the patients who met the criteria of liver depression and mental distress insomnia were selected and collected into the group.Random control study was conducted.The eligible cases were divided into three groups,44 cases in each group.In the course of treatment,3 cases in the traditional Chinese medicine group fell off,2 cases in the western medicine group fell off,4 cases in the combined medicine group fell off,0 cases were eliminated,and 123 cases were finally included.The traditional Chinese medicine group took Shumian capsule,the western medicine group took Osazepam tablets,and the combined medicine group took Shumian capsule and Osazepam tablets.Data were collected by TCM syndrome score table,PSQI scale,SAS scale and SDS scale.all the data obtained through clinical observation were analyzed by SPSS20.0 statistical software.the statistical results took P<0.05 as the testing standard,and the difference was statistically significant.Results:1.Through a one-month clinical observation,the total effective rate of sleep treatment in 41 patients in the traditional Chinese medicine group was 82.9%,that in the western medicine group was 78.6%,and that in the combined medicine group was 95%in 40 patients.By comparing the traditional Chinese medicine group and the western medicine group,the two groups P=0.000,the difference was statistically significant,and the results showed that the traditional Chinese medicine group was superior to the western medicine group.Compared with the traditional Chinese medicine group and the combined group,the two groups have p=0.497>0.05.indicating that the difference is not statistically significant.the results show that the combined group is superior to the traditional Chinese medicine group alone in treating insomnia.compared with the western medicine group and the combined group,the two groups have p=0.000,with statistically significant difference,the results show that the combined group has higher curative effect in treating insomnia within one month than the western medicine group alone.2.According to Pittsburgh Sleep Score Scale,the total effective rate of sleep therapy in the traditional Chinese medicine group was 83.721%in 41 patients,and that in the western medicine group was 84.211%in 42 patients.The total effective rate of the combined group in 40 patients is 91.428%.by comparing the traditional Chinese medicine group and western medicine,the two groups have p=0.079>0.05,indicating that the difference is not statistically significant.comparing the traditional Chinese medicine group and the combined group,the two groups have 0.009<0.05,indicating that the difference is statistically significant.the results show that the combined group is superior to the traditional Chinese medicine group alone in treating insomnia.comparing the western medicine group and the combined group,the two groups have p=0.000<0.05,and the difference is statistically significant,the results show that the treatment effect of the combined group is higher than that of the western medicine group alone.3.According to th e self-rating anxiety scale,the total effective rate of sleep treatment in the Chinese medicine group was 61.0%in 41 patients,and the total effective rate of insomnia treatment in the western medicine group was 64.3%in 42 patients.The total effective rate of the combined group in 40 patients is 85%.by comparing the traditional Chinese medicine group and the western medicine gfoup,the two groups have p?0.748>0.05,indicating that the difference is not statistically signif icant.comparing th e traditional Chinese medicine group and the combined group,the two groups have 0.000<0.05,indicating that the difference is statistically significant,the results show that the combined group is superior to the traditional Chinese medicine group alone in treating insomnia.comparing the western medicin e group and the combined group,the two groups have p=0.000<0.05,the difference is statistically significant.the results show that the treatment effect of the combined group is higher than that of the western medicine group alo ne.4.Through the analysis of the self-rating depression scale,it is found that the total effective rate of sleep treatm ent in the traditional Chinese medicine group is 61,0%in 41 patients,and the total effective rate of insomnia treatment in the western medicine group is 64.3%in 42 patients.The total effective rate of the combined group in 40 patients is 87.5%.by comparing the traditional Chinese medicine group and the western medicine group,the two groups have p?0.056>0.05,indicating that the difference is not statistically significant.comparing the traditional Chinese medicine group and the combined group,the two groups have 0.000<0.05,indicating that the difference is statistically significant.the results show that the combined group is superior to the traditional Chinese m edicine group alone in treating insomnia.comparing the western medicine group and the combined group,the two groups have p=0,000<0.05,the difference is statistically significant.the results show that the treatment effect of the combined group is higher than that of the western medicine group alone.Conclusion:In the one-month clinical observation,the TCM symptom score shows that the clinical efficacy of Shumian capsule and Shumian capsule combined with oxazepam tablets is equivalent,suggesting that the improvement of TCM symptoms of liver depression and mental distress insomnia may be related to the treatment of Shumian capsule.Pittsburgh Sleep Scale,Self-Rating Anxiety and Depression Scale and Self-Rating Depression Scale suggest that the therapeutic effect of combined drugs is higher than that of oxazepam tablets or Shumian capsules alone in the treatment period within one month,and no obvious adverse reactions are observed during the clinical observation period,which is worthy of clinical application. |
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