Correlative Research On Senile Degenerative Aortic Insufficiency, Diastolic Blood Pressure And TCM Syndromes

Objective:To explore the correlation between age,diastolic pressure and degree of aortic valve regurgitation in elderly patients with degenerative aortic insufficiency,and the correlation between the distribution of TCM syndromes and age,diastolic pressure and degree of aortic valve regurgitation.To provide a new clinical diagnostic and therapeutic thinking of traditional Chinese medicine for the clinical diagnosis and treatment of the related clinical symptoms caused by senile degenerative aortic insufficiency,delaying the degeneration of aortic valve,improving the function of diseased valve,improving the quality of life of patients,and improving diastolic blood pressure.Method:A total of 426 outpatients and inpatients in our hospital were randomly collected and 154 cases of senile degenerative aortic valve insufficiency were recorded.Their age,sex,related medical history and syndromes were recorded.According to the method of establishing related syndromes in Syndromes Differentiation,edited by Zhu Wenfeng,published by People's Health Publishing House in 2008.According to the tutor's clinical experience,12 cases of common disease and venereal syndrome elements and 5 basic disease location syndrome elements were included in the evaluation study.The syndrome types of syndrome elements were established,and the data were analyzed by R language 3.5.2 statistical software.Result:1.In 426 subjects,the age distribution of the control group and the case group was different(P<0.05).Age was regarded as a variable of grade classification.It was found that age was positively correlated with the incidence of the disease(P<0.05).2.154 elderly patients with degenerative aortic valve insufficiency were divided into age group and valvular regurgitation degree group as orderly classification data.Age was positively correlated with regurgitation degree(P<0.05).3.154 elderly patients with degenerative aortic insufficiency were divided into age group and diastolic pressure group as orderly classification data.It was found that the age of elderly patients with degenerative aortic insufficiency was negatively correlated with diastolic pressure level(P<0.05).4.In the case group,125 cases were diagnosed as nephropathy,83 cases as liver,67 cases as spleen,52 cases as heart and 23 cases as lung.Nephrotic location is closely related to senile degenerative aortic insufficiency,while pulmonary location is less related to the disease.5.In the case group,88 cases were diagnosed as deficiency of qi,37 cases were diagnosed as deficiency of blood,106 cases were diagnosed as deficiency of yin and 18 cases were diagnosed as deficiency of yang.Among the deficiency cases,the most were diagnosed as Yin deficiency,and the least were diagnosed as Yang deficiency.The incidence of Qi deficiency was the highest in 70-79 years old,followed by 80 years old and above,and the lowest in 65-69 years old.The incidence of blood deficiency diastolic blood pressure was higher in people with diastolic blood pressure lower than 70 mmHg than that of people with diastolic blood pressure higher than 70 mmHg.The incidence of Yang deficiency increased with the increase of age,the decrease of diastolic blood pressure and the aggravation of valve regurgitation.6.In the case group,there were 2 cases of qi stagnation syndrome,54 cases of phlegm-dampness syndrome,10 cases of blood stasis syndrome,32 cases of phlegm-blood stasis syndrome and 5 cases of phlegm-qi stasis syndrome,among which phlegm-dampness syndrome was the most common.Statistical analysis showed that the distribution of Qi stagnation and blood stasis syndrome was that the incidence of low diastolic blood pressure group was lower than that of high diastolic blood pressure group.7.In the case group,there were 17 cases of deficiency of qi,42 cases of deficiency of yin,7 cases of deficiency of yang,18 cases of deficiency of Qi and blood,53 cases of deficiency of Qi and yin,and 11 cases of deficiency of yin and yang.The distribution regularity of Qi deficiency syndrome is as follows:the incidence of diastolic pressure in 70-79 mmHg population>the incidence of diastolic pressure greater than or equal to 80 mmHg population>the incidence of diastolic pressure less than 70 mmHg population;the incidence of Yin deficiency syndrome tends to decrease with the increase of age,the decrease of diastolic pressure level and the aggravation of aortic valve regurgitation degree;the distribution regularity of Qi-blood deficiency syndrome is that the diastolic pressure is less than 70 mmHg population.The diastolic pressure was greater than or equal to 80 mmHg and the diastolic pressure was 70-79 mmHg.The distribution of Yin-Yang deficiency syndrome was mainly concentrated in those with diastolic pressure less than 70 mmHg and those with high degree of aortic valve regurgitation.8.In the study of the distribution of syndrome elements and related medical history in case group,the distribution of qi stagnation is negatively correlated with hypertension,the distribution of phlegm and dampness is positively correlated with cerebral infarction,the distribution of blood stasis is negatively correlated with hypertension and positively correlated with cerebral infarction.9.In the study of the distribution of TCM syndromes and related medical history in case group,the distribution of phlegm-dampness syndrome is positively correlated with hypertension,and the distribution of phlegm-blood stasis syndrome is positively correlated with cerebral infarction.Conclusion:1.The overall trend of the incidence of degenerative aortic insufficiency in the elderly increases with age.2.Age of elderly patients with degenerative aortic insufficiency is positively correlated with the degree of regurgitation.3.Age of elderly patients with degenerative aortic insufficiency is negatively correlated with diastolic blood pressure level.4.Nephrotic location is closely related to senile degenerative aortic insufficiency,while pulmonary location is less related to the disease.5.In the distribution of syndrome elements,the incidence of Qi deficiency is the highest in 70-79 years old,followed by 80 years old and above,and the lowest in 65-69 years old.The incidence of blood deficiency is closely related to the incidence of blood deficiency.The incidence of blood deficiency in people with diastolic pressure lower than 70 mmHg is higher than that of people with diastolic pressure higher than 70 mmHg;the incidence of Yang deficiency increases with the increase of age,the decrease of diastolic pressure and the aggravation of valve regurgitation.6.Empirical aspects mainly include qi stagnation syndrome,phlegm-dampness syndrome,blood stasis syndrome,qi stagnation and blood stasis syndrome,phlegm and blood stasis syndrome,phlegm and blood stasis syndrome,phlegm and blood stasis syndrome.Among them,phlegm-dampness syndrome is the most common,and the distribution of qi stagnation and blood stasis syndrome is that the incidence of low diastolic blood pressure is lower than that of high diastolic blood pressure.7.Deficiency syndrome mainly includes Qi deficiency syndrome,Yin deficiency syndrome,Yin deficiency syndrome,Qi-blood deficiency syndrome,Qi-Yin deficiency syndrome and Yin-Yang deficiency syndrome.The distribution regularity of Qi deficiency syndrome is as follows:the incidence of diastolic pressure in 70-79 mmHg population>the incidence of diastolic pressure greater than or equal to 80 mmHg population>the incidence of diastolic pressure less than 70 mmHg population;Yin deficiency syndrome with the increase of age,the decrease of diastolic pressure level and aortic valve regurgitation.The incidence of deficiency of both qi and blood tends to decrease with the aggravation of diastolic pressure;the distribution of deficiency of both qi and blood tends to be less than 70 mmHg;the incidence of diastolic pressure greater than or equal to 80 mmHg;the incidence of diastolic pressure between 70 and 79 mmHg;and the distribution of deficiency of yin and Yang tends to be mainly concentrated in those with diastolic pressure less than 70 mmHg and those with high degree of aortic valve regurgitation.8.The distribution of qi stagnation is negatively correlated with hypertension,phlegm-dampness is positively correlated with cerebral infarction,blood stasis is negatively correlated with hypertension and positively correlated with cerebral infarction.9.The distribution of phlegm-dampness syndrome is positively correlated with hypertension,and the distribution of phlegm-blood stasis syndrome is positively correlated with cerebral infarction.