Comparison Of The Anaesthesia Effect Of General Anaesthesia Assisted Ultrasound-guided Serratus Anterior Plane Block And Intercostal Nerve Block In Breast Cancer Surgery

Objective: To investigate the anesthetic effect,postoperative analgesic effect and safety of anterior serratus plane block and intercostal nerve block in patients undergoing modified radical mastectomy for breast cancer.Methods: Sixty patients undergoing modified radical mastectomy were randomized divided into two groups.The patients in group S were recevied Ultrasound-guided anterior serratus plane block before surgery,the patients in group I were recevied Ultrasound-guided intercostal nerve block before surgery,the patients in two groups were all received general anesthesia and patient-controlled intravenous analgesia(PCIA).The nerve block operation time,onset time,duration time,scope of analgesia were recorded.Total dosage of sufentanil,effective pressing times of PCIA,changes of VAS scores and complications were recorded in postoperation 48 hours.Results: Compared with group I,nerve block operation time were significantly reduced,duration time were significantly extended,scope of analgesia were significantly increased in group S(P<0.05).Compared with group I,total dosage of sufentanil and effective pressing times of PCIA were significantly decreased in group S(P<0.05).Compared with group I,VAS scores at rest and in activity 12 hours and 24 hours postoperatively were significantly decreased in group S(P<0.05).Nerve block working time,rescue analgesia rate,postoperative complications such as nausea,emisis,hypotension,bradycardia,respiratory depression and pneumothorax had no significant difference.Conclusion: For patients undergoing modified radical mastectomy,serratus anterior plane is more effective and safer than intercostal nerve block for postoperative analgesia,and postoperative analgesics were used less.