Efficacy Of Continuous Serratus Plane Block On Early Postoperative Quality Of Recovery And Analgesia For Breast Cancer Patients

Objective: to investigate the efficacy of ultrasound-guided continuous serratus plane block on early postoperative quality of recovery and analgesia after modified radical mastectomyMethod: sixty female patients of ASA I or II,aged 18 ~ 65 yr,weighing 45~80 kg scheduled for unilateral modified radical mastectomy under general anesthesia were randomly assigned into 3 groups(n=20 each).Group SPB received ultrasound-guided single serratus plane block with 30 ml of 0.33% ropivacaine and received patient-controlled intravenous analgesia after surgery,Group PCNA received ultrasound-guided continuous serratus plane block with patient-controlled nerve analgesia,with continuous infusion of 0.33% ropivacaine and 30 ml of0.33% ropivacaine for the first does.Group PCIA only received patient-controlled intravenous analgesia after surgery.The QoR-40 scores at 24h(T2)and 48h(T3)after surgery were recorded,resting numerical rating scale(NRS)pain scores,moter NRS pain scores at 6h(T4)、8h(T5)、12h(T6)、24h(T7)、48h(T8)after surgery,the times of pressing PCA pump and adverse effects were also recorded.Results: compared with group PCIA,The global QoR-40 scores were significantly increased,the resting and motor NRS pain scores at T4、T5、T6、T7、T8 were significantly lower in group SPB and PCNA(all P<0.01);Compared with group PCIA,the incidence of nausea and vomiting was decreased in group SPB and PCNA,the incidence of dizziness was decreased in group PCNA(all P<0.05).Conclusion: Ultrasound-guided continuous serratus plane block and serratus plane block can improve the early postoperative quality of recovery and provide good analgesia after modified radical mastectomy,enhance recovery after surgery.