| Objective:Discussed the differences in polysomnographic variables and complications between the patients with obstructive sleep apnea hypopnea syndrome who were first diagnosed with symptoms of different systemic diseases,and to determine the occurrence of complications of each related system,in order to improve the early diagnosis of patients with obstructive sleep apnea.Methods:Through retrospective study in January 2018-December 2018 by the Second hospital of Shanxi Medical University sleep monitoring center is confirmed 139 cases of hospitalized patients with OSAHS were divided into six groups according to their first inpatient department,including simple OSAHS group,the group of the first diagnosis was in the department of cardiology,the group of the the first diagnosis was in the department of neurology,the group of the the first diagnosis was in the department of nephrology,the group of the the first diagnosis was in the department of endocrinology,the group of the the first diagnosis was in the department of pneumology.Recording the general data including sex,BMI,first visit department,main diagnosis and chief complaint symptoms of patients in each group,and more detailed records the polysomnograph related data,including AHI,LAT,La S02,SLT90,Sa02 min.Analysing the composition of each group and the difference of PSG.According to the above data,it will obtain three clusters by cluster analysis,and analyzes the relationship between each cluster and the first inpatient department.Results:1 The simple OSAHS group:the number of OSAHS patients accounted for 25% of all OSAHS patients,and males were more than females,and the age(47.54±11.76vs57.50±12.29vs57.51±9.36vs48.21±14.21vs50.40±11.85vs58.71 ±14.06)was smaller than other groups,the difference was statistically significant(P<0.05).The AHI index level(42.48±25.43 vs18.41±13.95vs24.03±16.20vs33.50±22.02vs11.58±5.92vs39.91±22.69)was higher than other groups,the difference was statistically significant(P<0.05).The group of the first diagnosis was in the department of cardiology: the number of patients first diagnosed in the department of cardiology group accounted for 26% of all OSAHS patients,males were more than females,and the BMI level was higher than other groups(33.24±31.50vs28.80±4.19vs27.55±3.55vs31.19±4.71vs30.10±4.21vs31.28±4.39),the difference was statistically significant(P<0.05).The group of the the first diagnosis was in the department of neurology:the number of patients first diagnosed in the department of psychiatry group accounted for 27% of all OSAHS patients,with more males than females,and the BMI level was lower than that of other groups(27.55±3.55vs28.80±4.19vs33.24±31.50vs31.19±4.71vs30.10±4.21vs31.28±4.39),the difference was statistically significant(P<0.05).The group of the the first diagnosis was in the department of nephrology:the population accounts for 14% of all OSAHS patients,and males are more than fe males.Age(48.21±14.21vs47.54±11.76vs57.50±12.29vs57.51±9.36vs50.40±11.85vs58.71±14.06),BMI(31.19±4.71vs28.80±4.19vs33.24±31.50vs27.55±3.55vs30.10±4.21vs31.28±4.39),AHI(33.50±22.02vs42.48±25.43vs18.41±13.95vs24.03±16.20vs11.58±5.92vs39.91±22.69),LAT(48.86±18.31vs65.58±23.26vs44.17±20.82vs56.21±26.39vs34.52±13.00vs68.81±24.69)?LSa O2(76.65±9.54vs73.49±9.09vs79.67±8.78vs77.68±6.84vs82.40±1.67vs59.29±14.23)?SLT90(22.79±28.61vs29.07±27.56vs16.19±27.51vs17.14±22.51vs6.28±4.71vs64.80±33.94)and Sa O2min(92.86±2.38vs91.80±3.08vs92.72±3.98 vs 9 2.70±2.96vs94.40±2.30vs83.66±8.73)were at moderate levels in each group,with s tatistically significant differences(P<0.05).The group of the the first diagnosis was in the department of endocrinology:the number of patients with OSAHS accounted for 3% of all patients,and males were more than females.The AHI levels(11.58±5.92vs42.48±25.43vs18.41±13.95vs24.03±16.20vs33.50±22.02vs39.91± 22.69)? LAT(34.52±13.00vs65.58±23.26vs44.17±20.82vs56.21±26.39vs48.86±18.31 vs68.81±24.69),and SLT90(6.28±4.71vs29.07±27.56vs16.19±27.51vs17.14±22.51 vs 22.79±28.61vs64.80±33.94)were lower than other groups,and the difference was statistically significant(P<0.05).LSa O2(82.40±1.67vs73.49±9.09vs79.67±8.78vs77.68±6.84vs76.65±9.54vs59.29±14.23)and Sa O2min(94.40±2.30vs91.80±3.08vs92.72±3.98vs92.70±2.96vs92.86±2.38 vs 83.66±8.73)were higher than other groups,with statistically significant differences(P<0.05).The group of the the first diagnosis was in the department of pneumology:the number of OSAHS patients accounted for 5% of all OSAHS patients,males were more than females,and the age was larger than other groups(58.71±14.06vs47.54±11.76vs57.50±12.29vs57.51±9.36vs48.21±14.21vs50.40 ±11.85),the difference was statistically significant(P<0.05).LAT(68.81±24.69vs65.58±23.26vs44.17±20.82vs56.21±26.39vs48.86±18.31vs34.52±13.00)and SLT90(64.80±33.94vs29.07±27.56vs16.19±27.51vs17.14±22.51vs22.79±28.61vs6.28±4.71)were both higher than other groups,with statistically significant differences(P<0.05).LSa O2(59.29±14.23vs73.49±9.09vs79.67±8.78vs77.68±6.84vs76.65±9.54vs82.40±1.67)and Sa O2min(83.66±8.73vs91.80±3.08vs92.72±3.98vs92.70±2.96vs92.86±2.38vs94.40±2.30)were lower than other groups,with statistically significant differences(P<0.05).2 Cluster1: severe and middle-aged obese patients,and the levels of AHI(64.97±12.48vs29.96±11.52vs17.32±11.44),LAT(78.96±19.75vs73.67±21.27vs39.98±13.41)and SLT90(54.73±26.65vs41.59±31.86vs6.42±7.57)were all higher than other clusters,with statistically significant differences(P<0.05).LSa O2(67.35±7.83vs68.69±8.97vs82.29±4.94)and Sa O2min(88.72±5.48vs89.59±4.64vs94.04±1.51)were lower than other clusters,with statistically significant differences(P<0.05); Cluster2:moderate and middle-aged obese patients,AHI(29.96±11.52vs64.97±12.48vs17.32±11.44),LAT(73.67±21.27vs78.96±19.75vs39.98±13.41),SLT90 level(41.59±31.86vs54.73±26.65vs6.42±7.57),LSa O2(68.69±8.97vs67.35±7.83vs82.29±4.94),Sa O2min(89.59±4.64vs88.72±5.48vs94.04±1.51)were moderate compared with cluster 1and 3,with statistically significant difference(P<0.05).Cluster3:slight and middle-aged obese patients,The AHI(17.32±11.44vs64.97±12.48vs29.96±11.52),LAT(39.98±13.41vs78.96±19.75vs73.67±21.27)and SLT90(6.42±7.57vs54.73±26.65vs41.59±31.86)of were all lower than other clusters,with statistically significant differences(P<0.05).LSa O2(82.29±4.94vs67.35±7.83vs68.69±8.97)and Sa O2min(94.04±1.51vs88.72±5.48vs89.59±4.64)were higher than other subtypes,with statistically significant differences(P<0.05).Comparison between subgroup 1 and subgroup 2: except the differences in age and AHI were statistically significant(P<0.05),the remaining indicators were all P>0.05,and the differences were not statistically significant.Comparison between cluster 1 and cluster 3: except for age,sex and BMI,the remaining indicators were all P<0.05,with statistically significant differences.Comparison between subgroup 2 and subgroup 3: except for age,sex and BMI,the remaining indicators were all P<0.05,and the difference was statistically significant.Conclusion:1 The degree of hypoxia in the patients first diagnosed with respiratory diseases in the respiratory department was worse than that in the OSAHS group.2 AHI as the main index cannot fully assess the severity of OSAHS damage to related target organs;3 Currently,the public and clinicians still have insufficient understanding of the harm degree of osahs-related target organ diseases. |
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