Meta-analysis Of Short-term Efficacy Of Precise Hepatectomy And Traditional Hepatectomy For Primary Liver Cancer

Objective:To explore the safety and effectiveness of precise hepatectomy in the treatment of primary liver cancer.Methods:The literatures about precise hepatectomy and traditional hepatectomy for primary liver cancer were retrieved from CNKI,WanFang Data Knowledge Service Platform,VIP,PubMed,Cochrane Library and Web of Science database.Results:A total of 33 articles were included in the study,including 3987 patients,2102 in the precision group and 1885 in the traditional group.Meta analysis results showed that compared with the traditional group,the operation time of the precision group was prolonged(MD=31.77,P<0.00001),while the intraoperative blood loss(MD=-173.50,P<0.00001),and the length of hospital stay(MD=-4.55,P<0.00001),postoperative liver function indicators of aspartate aminotransferase AST(MD=-27.76,P<0.00001),alanine aminotransferase ALT(MD=-56.99,P<0.00001),total bilirubin TBiL(MD=-4.79,P<0.00001),serum albumin ALB(MD=6.63,P<0.00001),postoperative complication rate(OR=0.34,P<0.00001),positive margin of specimen resection(OR=0.31,P<0.00001),recurrence and metastasis rate(OR=0.62,P<0.0001)and Surgical 1-year survival rate(OR=1.80,P<0.00001)has advantages.Conclusion:Hepatectomy based on the concept of precision surgery is a safe and effective method for the treatment of primary liver cancer.It can reduce the amount of intraoperative bleeding,reduce the risk of surgery,reduce the incidence of postoperative complications,improve the quality of life of patients with prognosis,and have better short-term effects.