Analysis Of Imaging Features And Risk Factors In Young Patients With Cerebral Infarction

This research is mainly divided into two parts.The first part is to evaluate the imaging changes of cervical vessels in young patients with cerebral infarction and compared with those without cerebral infarction based on CTA and MRI,and to study the correlation between the cerebral infarction area,length and stenosis degree of carotid artery plaques in case group,and to explore the role of cervical vascular imaging changes in evaluating the etiological,treatment and prognosis in young patients with cerebral infarction.The second part analyzes the risk factors,OR value of risk factors by Logistic regression based on the clinical history,laboratory examinations and imaging changes to intervene effectively and improve the prognosis.Part One Analysis of imaging characteristics of young patients with cerebral infarctionObjective:To evaluate the imaging characteristics of carotid artery in young patients with cerebral infarction and to analyze the correlation between the area and length of carotid plaque and the degree of carotid stenosis.Method:A retrospective study was conducted to collect young patients who underwent neck CTA examination from January 2014 to December 2018.They were examined by cranial MRI one week before or after admission.According to the results of cranial MRI,they were divided into acute cerebral infarction group(case group),non-cerebral infarction group(control group).The number,length,distribution,nature and degree of stenosis of carotid plaques detected by CTA in the two groups were observed and analyzed.The correlation between the area of cerebral infarction and the number and length of carotid artery plaques and the degree of stenosis was analyzed in the case group.Result:A total of 352 cases were retrospectively analyzed,including 96 cases in case group,212 cases in control group and 44 cases excluded.There were statistical differences in the detection of carotid plaque,its nature and degree of stenosis between the case group and the control group,but no statistical difference in the plaque distribution.In the case group,there was a correlation between the area of cerebellar infarction and the length of plaque and the degree of vascular stenosis,and a weak correlation between the size and the number of plaque.Conclusion:Neck CTA examination of young patients with cerebral infarction can effectively detect the cervical vascular plaques and immediately judge their nature,clearly show the distribution of plaques and the stenosis of the corresponding vessels,and determine the correlation between the size of cerebral infarction and the length and number of carotid plaques and the degree of stenosis.It plays an important role in etiological judgment,treatment and prognosis.Part Two Risk factors analysis of young patients with cerebral infarctionObjective:By analyzing the risk factors of young patients with cerebral infarction based on the clinical history,imaging changes and laboratory examinations to achieve the purpose of early detection,early prevention and early intervention,and provide scientific basis for the prevention and treatment of young patients with cerebral infarction.Method: A retrospective study was conducted to collect young patients who underwent neck CTA examination from January 2014 to December 2018.They were examined by cranial MRI one week before or after admission.According to the results of cranial MRI,they were divided into acute cerebral infarction group(case group),non-cerebral infarction group(control group).The clinical history,imaging changes and laboratory examinations of patients were collected,and the influencing factors of the study were grouped and assigned.After univariate regression analysis was carried out to get meaningful influencing factors,multivariate regression analysis was carried out to get P and OR values.Result:(1)Univariate regression analysis: The P values of age,sex,BMI,carotid artery plaque and stenosis degree,hypertension,diabetes,hyperlipidemia,hyperuricemia,hyperhomocysteine,smoking history and drinking history were found to be less than 0.05,indicating that the differences were statistically significant.(2)Multivariate regression analysis: Gender,degree of vascular stenosis,BMI,hypertension,high uric acid,high homocysteine and smoking history were statistically significant,and the OR values respectively were 6.230,3.949,4.454,6.077,5.210,5.450 and 8.143.Conclusion:some controllable risk factors,which include BMI,carotid plaque,carotid stenosis,hypertension,diabetes mellitus,hyperlipidemia,hyperuricemia,hyperhomocysteine,smoking history and drinking history in young patients with cerebral infarction,need early detection and intervention.We must actively improve risk factors,and pay attention to the superposition effect of several risk factors,to reduce the incidence of young cerebral infarction,improve the prognosis and quality of life.