The Risk Factors Of Microembolism After The Endovascular Coiling Of Unruptured Intracranial Aneurysms

Objective:To discuss the risk factors of microembolism after the endovascular coiling of UIA.Methods:Between March 2018 and February 2019,110 UIAs in110 patients underwent both coiling and posttreatment MRI-DWI.A ccording to the abnormalities on DWI,the patients were divided into positive group and negative group.Single factor statistical analysis a nd multivariate analysis were then performed to identify the reason o f microembolism and the independent risk factors for developing micr oembolism following the coiling of an aneurysm.Results:Microembolic lesions were noted in 56 of 110 patients(50.9%).The results of the multivariate analysis showed that the foll owing factors significantly influenced the risk for microembolism:histo ry of hypertension(OR=2.909,P=0.015,95%CI:1.233~6.862),the b igger Aneurysm dome size(OR=2.590,P=0.033,95%CI:1.078~6.222),clopidogrel resistance(OR=4.369,P=0.010,95%CI:1.419~13.456)and stent-assisted coiling(OR=3.474,P=0.045,95%CI: 1.029~11.724).Conclusion:The incidence of microembolism after endovascular c oiling of UIA was not low.Microembolism occurred more frequently in patients with hypertension,the bigger Aneurysm dome size,clopid ogrel resistance and stent-assisted coiling.Patients with risk factors sh ould be emphasized and treated in a targeted manner may reduce the incidence of microembolism.