| Objective:This topic based on the theory of "brain-intestinal connection",took the cases of heart-spleen deficiency type of insomniac for research object.In order to observe the effect of acupoint catgut embedding application of abdominal-acupuncture therapy on the content of serum 5-hydroxytryptamine(5-HT)and its clinical effect.We need to find an effective and convenient way to treat insomnia.Methods:According to the inclusion criteria and exclusion criteria,66 patients with heart-spleen deficiency type of insomnia were randomly divided into the treatment group and the control group,which were from Fujian Provincial People’s Hospital.Among them,60 patients were actually completed due to the missing or deleting patients.There were 30 patients in the treatment group and 30 patients in the control group.In the treatment group,the patients received acupoint catgut embedding application of abdominal-acupuncture therapy once in 2weeks,and two weeks for a course of treatment.In the control group,the patients received conventional acupuncture once two days,and 7 times(2 weeks)for a course of treatment.Both groups received 2 courses of continuous treatment.The changes of patients’ PSQI score,traditional Chinese medicine(TCM)symptom and sign score and 5-HT in serum before and after treatment,were observed and evaluated curative effect.The data was counted by SPSS22.0.P<0.05 was considered to be statistically significant.Results:1.The total effective rate of the treatment group was 90.00%,the recovery and remarkable response rate of the treatment group was 80.00%.The total effective rate of the control group was 86.66%,the recovery and remarkable response rate of the control group was 50.00%.The result showed that the treatment group was better than the control group(P<0.05).2.After two courses of continuous treatment,the PSQI each factor score and total score were lower than before treatment in both groups(P<0.05).By comparison,the treatment group was better than the control group in increasing sleep time(P<0.05).There was no significant difference between the two groups in improving sleep quality,onset time,sleep efficiency,sleep disorders and daytime dysfunction(P>0.05).3.After two courses of continuous treatment,the TCM symptom and sign score of patients was all decreased compared with before treatment in both groups(P<0.05).By comparison,there was no statistically significant difference in the score of TCM symptom and sign between the two groups(P>0.05).4.After two courses of continuous treatment,the serum 5-HT level of patients in both groups was increased than before treatment(P<0.05).By comparison,the increase of serum5-HT level in the treatment group was higher than that in the control group(P<0.05).5.Before treatment,there was a negative correlation between serum 5-HT level and PSQI score(P<0.05).6.There was no significant relationship between serum 5-HT level and TCM symptom and sign score before treatment(P>0.05).Conclusion:Both the treatment group and the control group can improve the symptom of heart-spleen deficiency type of insomnia,and the treatment group has a better effect.The treatment group is better than the control group in increasing sleep time and serum 5-HT.The result showed that the lower serum 5-HT level,the higher PSQI score,and the more severe insomnia symptom. |